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Office
75 Francis St
ASB II, 3rd Floor
Boston, MA 02115Phone+1 617-732-5997Fax+1 617-734-0336
Summary
- Experience Summary
James is a board-certified colorectal surgeon with a specific emphasis on minimally invasive techniques. The mission of his practice is to leverage his academic, research and clinical interests to provide innovative surgical care. James has an active research laboratory and was an early adaptor of laparoscopic colorectal procedures beginning in mid-2000. He was the first to perform combined endo-laparoscopic surgery (CELS) on the West Coast. This is a novel technique used to remove benign polyps that are not removeable with standard endoscopic procedures and would typically require a bowel resection.
James was recruited by Brigham Women’s Hospital (Boston, MA) in 2019. His clinical practice and research focuses on colorectal cancer and inflammatory bowel disease. He remains interested in developing novel approaches for less invasive procedures and to promote faster patient recovery. James is also the Associate editor for the Journal of Surgical Research to which he contributes his findings and experience helping the medical field further innovative techniques.
Education & Training
- New York Presbyterian Hospital (Cornell Campus)Residency, Colon and Rectal Surgery, 2004 - 2006
- Beth Israel Deaconess Medical CenterResidency, Surgery, 1998 - 2004
- Harvard Medical SchoolFellowship, Mucosal Pathobiology, 2000 - 2002
- Beth Israel Deaconess Medical CenterInternship, Surgery, 1997 - 1998
- Mt. Sinai School of MedicineMD, Medicine, 1994 - 1997
- Icahn School of Medicine at Mount SinaiClass of 1997
- Brown UniversitySc.B, Biology, 1989 - 1993
Certifications & Licensure
- MA State Medical License 2014 - 2026
- ME State Medical License 2021 - 2025
- NH State Medical License 2021 - 2023
- CA State Medical License 2006 - 2013
- NY State Medical License 2004 - 2007
- American Board of Colon and Rectal Surgery Colon & Rectal Surgery
- American Board of Surgery Surgery
- American Board of Colon and Rectal SurgeryDiplomat
Awards, Honors, & Recognition
- Boston University Questrom School of Business Leadership Development (invited Participation) Tuffs University, 2018
- Accomplished Teaching, Surgery Clerkship Tuffs University School of Medicine, 2016
- Hero of the Month Colon Cancer Alliance, 2015
Publications & Presentations
PubMed
- Colorectal Cancer-Associated Myofibroblasts Exhibit Enhanced Angiogenin Expression and Signaling via the PLXNB2 Receptor.Alexander Hu, Yulia I Nussbaum, Jonathan Mitchem, James Yoo
The Journal of Surgical Research. 2024-04-01 - 10 citationsBioprinting Au Natural: The Biologics of Bioinks.Kelsey Willson, Anthony Atala, James J. Yoo
Biomolecules. 2021-10-28 - 1 citationsThe Association Between Sex and Survival for Anal Squamous Cell Carcinoma.Vanessa M. Welten, Adam C. Fields, Robert A. Malizia, James J. Yoo, Jennifer Irani
The Journal of Surgical Research. 2021-08-20
Authored Content
- “Hand-Assisted Laparoscopic Sigmoidectomy for Recurrent Diverticulitis” Available through the Cine-Med ACS Video Library for purchase (Product ID: ACS-2363)June 2005
- 51-year-old Renal Transplant Recipient with Abdominal PainMarch 2020
- Progressive Primary Appendiceal Crohn’s Disease in a 21-year-old FemaleMarch 2020
- Plummer R**, Sekigami Y, Chen L, Yoo J. Epiploic appendagitis mimicking recurrent diverticulitis. Case Reports in Surgery, Volume 2018 (2018), Article ID 1924067January 2018
- “The Robot Has No Role in Elective Colon Surgery”February 2014
- “Academic Colorectal Surgery”, Yoo J. Clin Colon Rectal Surg. 2014; 27:39-40.January 2013
- “Laparoscopic-Assisted Sigmoid Polypectomy Using CO2 Colonoscopy”May 2005
- “Extending the Limits of Transanal Excision Using Laparoscopy”. Available through Cine-ACS Video Library for purchase (Prod.iD ACS-2360May 2005
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Press Mentions
- No Coil® Placement in Patients Undergoing Left Hemicolectomy and Low Anterior Resection for Colorectal CancerDecember 10th, 2020
Committees
- Oversight Committee, Brigham and Women's Hospital Department of Surgery Research 2020 - Present
Research History
- Brigham and Women’s Hospital Surgeon, Division of Gastrointestinal and General SurgeryPeer Review: Analysis of Electronic Residency Application Service (ERAS) Data Can Improve House Staff Diversity. Geary A**, Wang V, Cooper J, Roberts K, Yoo J. J Surg Res. 2021; 257: 246-2512021 - 2021
- Brigham and Women’s Hospital Surgeon, Division of Gastrointestinal and General SurgeryPeer Review: Surgical Resection Improves Overall Survival of Patients with Small Bowel Leiomyosarcoma Welten VM, Fields AC, Lu PW, Yoo J, Goldberg JG, Irani J, Bleday R, Melnitchouk N. Accepted for publication in International Journal of Colorectal Disease, 2020.2020 - 2020
- Brigham and Women’s Hospital Surgeon, Division of Gastrointestinal and General SurgeryPeer Review: Surgical Resection Improves Overall Survival of Patients with Small Bowel Leiomyosarcoma Welten VM, Fields AC, Lu PW, Yoo J, Goldberg JG, Irani J, Bleday R, Melnitchouk N. Accepted for publication in International Journal of Colorectal Disease, 2020.2020 - 2020
- Brigham and Women’s Hospital Surgeon, Division of Gastrointestinal and General SurgeryPeer Review: Colorectal Sarcomatoid Carcinoma: A Rare Condition with Poor Outcomes. Welten VM, Lu PW, Fields AC, Yoo J, Melnitchouk N. Accepted as a research communication in Journal of GI Surgery, 2020.2020 - 2020
- Brigham and Women’s Hospital Surgeon, Division of Gastrointestinal and General SurgeryPeer Review: Sociodemographic Predictors of Surgery Refusal in Patients with Stage I-III Colon Cancer. Lu PW, Fields AC, Yoo J, Irani J, Goldberg JE, Bleday R, Melnitchouk N. Accepted in Journal of Surgical Oncology, 2020.2020 - 2020
- Brigham and Women’s Hospital Surgeon, Division of Gastrointestinal and General SurgeryPeer Review: Plummer R**, Hu GF, Liu T, Yoo J. Angiogenin Regulates PKD activation and COX-2 Expression induced by TNF-α and Bradykinin in the Colonic Myofibroblast. Biochemical and Biophysical Research Communications, 2020; 525(4): 870-876.2020 - 2020
- Brigham and Women’s Hospital Surgeon, Division of Gastrointestinal and General SurgeryPeer Review: Treatment of Stage I-III Rectal Cancer: Who is refusing surgery? Accepted in Journal of Surgical Oncology, 2020.2020 - 2020
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: Plummer R**, Papageorge M**, Ciomek N, Liu T, Yoo J. Myofibroblasts Enhance Tumor Growth in a Novel Mouse Model of Colorectal Cancer. J Surg Res. 2019; 244: 374-381.2019 - 2019
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: Jayaram A, Barr N, Plummer R**, Yao M, Chen L, Yoo J. Combined Endo-Laparoscopic Surgery (CELS) for Benign Colon Polyps: A Single Institution Cost Analysis. Surg Endosc. 2019 Oct;33(10):3238-3242. doi: 10.1007/s00464-018-06610-z. Epub 2018 Dec 3.2018 - 2018
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: Roper J, Tammela T, Cetinbas N, Akkad A, Almeqdadi M, Wu K, Sanchez-Rivera F, Rickelt S, Park Y, Liang X, Oberli M, Eng G, Roghanian A, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Bass A, Suarez Y, Yoo J, Chen L, Taylor MS, Zukerberg L, Katajisto P, Lees J, Deshpande V, Chen2017 - 2017
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: Younkin M, Kiely MX, Chen L, Yoo J. Prevalence of Colorectal Cancer in Young Patients with Isolated Bright Red Blood Per Rectum (BRBPR). Am J Dig Dis 2017; 4(1):6-122017 - 2017
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of Surgery28. Chu E**, Saini S**, Liu T, Yoo J. Bradykinin Stimulates Protein Kinase D–mediated Colonic Myofibroblast Migration via COX-2 and Hsp27. J Surg Res. 2017;209:191-198.2017 - 2017
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: Chu E**, Saini S**, Liu T, Yoo J. Bradykinin Stimulates Protein Kinase D–mediated Colonic Myofibroblast Migration via COX-2 and Hsp27. J Surg Res. 2017;209:191-198.2017 - 2017
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: Saini S**, Liu T, Yoo J. TNF-α Stimulates Colonic Myofibroblast Migration via COX-2 and Hsp27. J Surg Res. 2016; (204) 145-152.2016 - 2016
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: Khalil HA**, Kobayashi M, Rana P, Wagner JP, Scott A, Yoo J, Dunn JC. Mouse model of endoscopically ablated enteric nervous system. J Surg Res. 2016; 200(1): 117-121.2016 - 2016
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: Khalil HA**, Lei NY, Nie W, Lewis M, Stelzner M, Martin MG, Dunn J, Yoo J. Primary Myofibroblasts Maintain Short-Term Viability Following Submucosal Injection in Syngeneic, Immune-Competent Mice Utilizing Murine Colonoscopy. PLoS One, 2015 May 27;10(5):e0127258.2015 - 2015
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: Hill AL**, Sumra KK, Russell MM, Yoo J, Ko CY, Hart S, Wainberg Z, Hecht JR, Lin AY. A single institution experience in compliance with universal screening for lynch syndrome in colorectal cancer. J Gastrointest Surg. 2015 Mar; 19(3):543-50.2015 - 2015
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: Larson ES**, Khalil HA**, Lin AY, Russell M, Ardehali A, Ross D, Yoo J. Diverticulitis Occurs Early After Lung Transplantation, J Surg Res. 2014; 190(2): 667-71.2014 - 2014
- Tufts Medical Center Division Chief of Colorectal Surgery and Vice Chair of the Department of SurgeryPeer Review: O’Leary E, Larson E**, Lin AY, Reardon S, Lee P, Russell M, Melnitchouk N, Hart S, Ghassemi K, Hecht JR, Wainberg Z, Yoo J. A Multi-Disciplinary Cancer Program Enhances Hereditary Colorectal Cancer Detection. Am J Dig Dis. 2014; 1(1):62-66.2014 - 2014
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: Khalil H**, Nie W, Edwards RA, Yoo J. Isolation of Primary Myofibroblasts from Mouse and Human Colon Tissue. J Vis Exp. 2013; Oct 12;(80).2013 - 2013
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: Yoo J, Rodriguez Perez CE**, Nie W, Sinnett-Smith J, Rozengurt E. TNF-α and LPA Promote Synergistic Expression of COX-2 in Human Colonic Myofibroblasts: Role of LPA-mediated Transactivation of Upregulated EGFR. BMC Gastroenterology 2013; 20: 13(1): 90.2013 - 2013
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: Lee MK, Chen F, Esrailian E, Russell MM, Sack J, Lin AY, Yoo J. Combined Endoscopic and Laparoscopic Surgery (CELS) May Be an Alternative to Bowel Resection for the Management of Colon Polyps Not Removable by Standard Colonoscopy”. Surg Endosc. 2013; 27(6): 2082-6.2013 - 2013
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: Yoo J, Rodriguez Perez CE**, Nie W, Edwards RA, Sinnett-Smith J, Rozengurt E. TNF-α Induces UpRegulation of EGFR Expression and Signaling in Human Colonic Myofibroblasts. Am J Physiol Gastrointest Liver Physiol 2012; 302(8): G805-14.2012 - 2012
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: Yoo J, Rodriguez Perez CE**, Nie W, Sinnett-Smith J, Rozengurt E. Protein Kinase D1 Mediates Synergistic MMP-3 Expression induced by TNF-α and Bradykinin in Human Colonic Myofibroblasts. Biochem Biophys Res Commun. 2011; 413(1):30-5.2011 - 2011
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: Yoo J, Rodriguez Perez CE**, Nie W, Sinnett-Smith J, Rozengurt E. Protein Kinase D1 Mediates Synergistic MMP-3 Expression induced by TNF-α and Bradykinin in Human Colonic Myofibroblasts. Biochem Biophys Res Commun. 2011; 413(1):30-5.2011 - 2011
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: Rodriguez Perez CE**, Nie W, Sinnett-Smith J, Rozengurt E, Yoo J. TNF-α Potentiates Lysophosphatidic acid-induced COX-2 Expression via PKD in Human Colonic Myofibroblasts. Am J Physiol Gastrointest Liver Physiol 2011; 300(4): G637-46.2011 - 2011
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: Cabot JC, Lee SA, Yoo J, Nasar A, Whelan RL, Feingold DL. Long-Term Consequences of Not Closing the Mesenteric Defect After Laparoscopic Right Colectomy. Dis Colon Rectum 2010; 53: 289-292.2010 - 2010
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: Yoo J, Chung C, Slice L, Sinnett-Smith J, Rozengurt E. Protein kinase D mediates synergistic expression of COX-2 induced by TNF-α and bradykinin in human colonic myofibroblasts. Am J Physiol Cell Physiol 2009; 297(6): C1576-87.2009 - 2009
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: 12. Offodile AC, Lee SW, Yoo J, Whelan RL, Moradi D, Baxter R, Arnell TD, Nasar A, Sonoda T, Milsom JW, Feingold DL. Does Prior Abdominal Surgery Influence Conversion Rates and Outcomes of Laparoscopic Right Colectomy in Patients with Neoplasia? Dis Colon Rectum. 2008; 51(11):1669-74.2008 - 2008
- UCLA, Chief of the Section of Colorectal Surgery, Division of General Surgery, Co-Director of the UCLA Colorectal Cancer ProgramPeer Review: Lee SW, Yoo J, Dujovny N, Sonoda T, Milsom JW. Laparoscopic vs. Hand-Assisted Laparoscopic Sigmoidectomy for Diverticulitis. Dis Colon Rectum 2006; 49: 1-6.2006 - 2006
- General Surgery Resident, BIDMCPeer Review: Del Castillo IC, Fedor-Chaiken M, Song JC, Starlinger V, Yoo J, Matlin KS, Matthews JB. Dynamic Regulation of NKCC1 Surface Expression by Protein Kinase C-epsilon in Chloride Secretory Epithelia. Am J Physiol Cell Physiol 2005; 289(5):C1332-42.2005 - 2005
- General Surgery Resident, BIDMCPeer Review: Mammen JM, Song JC, Yoo J Kim PS, Davis HW, Calvo MI, Worrell RT, Matlin KS, Matthews JB. Differential Subcellular Targeting of PKC-epsilon in Response to Pharmacological or Ischemic Stimuli in Intestinal Epithelia. Am J Physiol Gastrointest Liver Physiol. 2005; 288(1): G135-142.2005 - 2005
- General Surgery Resident, BIDMCPeer Review: Mammen JM, Song JC, Yoo J Kim PS, Davis HW, Calvo MI, Worrell RT, Matlin KS, Matthews JB. Differential Subcellular Targeting of PKC-epsilon in Response to Pharmacological or Ischemic Stimuli in Intestinal Epithelia. Am J Physiol Gastrointest Liver Physiol. 2005; 288(1): G135-142.2005 - 2005
- Chief Resident, Surgery, Beth Israel Deaconess Medical CenterPeer Review: Yoo J, Nichols A, Mammen J, Calvo I, Song JC, Worrell RT, Matlin K, Matthews JB. Bryostatin-1 Enhances Barrier Function in T84 Epithelia through PKC-dependent Regulation of Tight Junction Proteins. Am J Physiol Cell Physiol. 2003; 285(2): C300-309.2003 - 2003
- Cheid Resident, Surgery, Beth Israel Deaconess Medical CenterPeer Review: Yoo J, Nichols A, Song JC, Mammen J, Calvo I, Worrell RT, Cuppoletti J, Matlin K, Matthews JB. Bryostatin-1 Attenuates TNF-Induced Epithelial Barrier Dysfunction: Role of novel PKC isozymes. Am J Physiol Gastrointest Liver Physiol 2003; 284(4): G703-712.2003 - 2003
- Chief Resident, Surgery - Beth Israel Deaconess Medical CenterPeer Review: Del Castillo IC, Alvarez JG, Freedman SD, Ollero M, Claros L, Song JC, Yoo J, Matthews JB. Docosahexaenoic acid selectively augments muscarinic stimulation of epithelial Cl(-) secretion. J Surg Res. 2003; 110(2): 338-43.2003 - 2003
- University of Cinncinati, Research FellowshipPeer Review: Yoo J, Nichols A, Song JC, Mun EC, Matthews JB. PKCε Dampens the Secretory Response of Model Intestinal Epithelia During Ischemia. Surgery 2001; 130(2): 310-318.2001 - 2001
- General Surgery Resident, BIDMCPeer Review: Gibson GR, Lesnikoski BA, Yoo J, Mott LA, Cady B, Barth RJ Jr. A Comparison of Ink Directed and Traditional Whole-Cavity Re-excision for Breast Lumpectomy Specimens with Positive Margins. Ann Surg Oncol 2001; 8 (9): 693-704.2001 - 2001
- Medical Student Icahn School of Medicine, Mount SinaiPeer Review: Yoo J, Chen H, Kraus T, Hirsch D, Polyak S, George I, Sperber K. Altered Cytokine Production and Accessory Cell Function After HIV-1 Infection. J Immunology. 1996; 157: 1313-1320.1996 - 1996
- Medical Student, Icahn School of Medicine, Mount SinaiPeer Review: Louie M, Yoo J, Moran T, Mayer L, Sperber K. Impairment of Monocytic Function after Influenza Virus Infection. Clin Diagn Lab Immunol. 1995; 2(4): 426-433.1995 - 1995
- Undergraduate student, Brown UniversityPeer Review: Yoo J, Ellis R, Morgan KG, Hai C. Mechanosensitive modulation of myosin phosphorylation and phosphatidylinositol turnover in smooth muscle. Am J Physiol Cell Physiol. 1994; 267(36): C1657-1665.1994 - 1994
Professional Memberships
- Fellow
- Member
- Association for Academic SurgeryMember
- Institutional Representative ProgramLeadership Committee
- Member
- Society for Surgery of the Alimentary Tract - Research CommitteeMember
- Society of University SurgeonsEquity, Diversity and Inclusion Committee
- Boston Surgical Society - Executive Council, Dinner ChairMember
- Society of Asian Academic SurgeonsMember
- New England Surgical SocietyMember
- Crohn's and Colitis Foundation Surgery Research Network - Institutional RepresentativeMember
- NSQIP-IBD - Colorectal ChampionMember
- Massachusetts Chapter of the ACS - Colorectal ChampionMember
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