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Office
3471 5th Ave
Ste 810
Pittsburgh, PA 15213Phone+1 412-692-4920
Summary
- Tim Greenamyre is the Love Family Professor and Vice-Chair of Neurology, chief of Movement Disorders, and Director of the Pittsburgh Institute for Neurodegenerative Diseases (PIND) and the American Parkinson Disease Association Advanced Center for Parkinson’s Disease Research at the University of Pittsburgh. He is a member of the Executive Advisory Board of the Michael J. Fox Foundation, and a member of the scientific advisory boards of the Parkinson’s Disease Foundation and the American Parkinson Disease Association. He has been listed as one of the ‘Best Doctors in America’ since the mid-1990s. He is editor-in-chief of the scientific journal Neurobiology of Disease and of MedLink Neurology (www.medlink.com). His laboratory studies mechanisms of neurodegeneration in Parkinson’s disease, with a focus on mitochondria. Translational studies use ‘gene therapy’ approaches and harness viral vectors for delivery into the brain.
Education & Training
- University of MichiganResidency, Neurology, 1987 - 1990
- University of MichiganInternship, Internal Medicine, 1986 - 1987
- University of Michigan Medical SchoolClass of 1986
Certifications & Licensure
- PA State Medical License 2004 - 2024
- FL State Medical License 2019 - 2021
- GA State Medical License 1995 - 2005
- NY State Medical License 1990 - 1996
- MI State Medical License 1986 - 1990
- American Board of Psychiatry and Neurology Neurology
Publications & Presentations
PubMed
- 1 citationsLRRK2 regulates production of reactive oxygen species in cell and animal models of Parkinson's disease.Matthew T Keeney, Emily M Rocha, Eric K Hoffman, Kyle Farmer, Roberto Di Maio
Science Translational Medicine. 2024-10-02 - NADPH oxidase 2 activity disrupts Calmodulin/CaMKIIα complex via redox modifications of CaMKIIα-contained Cys30 and Cys289: Implications in Parkinson's disease.Filippo Pullara, Madison C Forsmann, Ignacio J General, Joseph C Ayoob, Emily Furbee
Redox Biology. 2024-09-01 - 4 citationsLRRK2 kinase inhibition protects against Parkinson's disease-associated environmental toxicants.Neda M Ilieva, Eric K Hoffman, Mohammed A Ghalib, J Timothy Greenamyre, Briana R De Miranda
Neurobiology of Disease. 2024-06-15
Journal Articles
- New Frontiers in Parkinson's Disease: From Genetics to the ClinicJ. Timothy Greenamyre, MD, The Journal of Neuroscience
- Evidence for Compartmentalized Axonal Mitochondrial Biogenesis: Mitochondrial DNA Replication Increases in Distal Axons as an Early Response to Parkinson's Disease-Rel...J Timothy Greenamyre, Sarah B Berman, The Journal of Neuroscience
Grant Support
- Mtdna Damage As A Biomarker For Environmental Mitochondrial ToxicityNational Institute Of Environmental Health Sciences2011
- Mitochondrial Proteins In Parkinson'S DiseaseNational Institute Of Neurological Disorders And Stroke2009–2011
- Mechanisms &Consequences Of Iron Accumulation In PDNational Institute Of Neurological Disorders And Stroke2009–2011
- Administrative CoreNational Institute Of Neurological Disorders And Stroke2009–2011
- Gene-Environment Interactions In Transgenic RAT Models Of Parkinson DiseaseNational Institute Of Environmental Health Sciences2009–2010
- Screening Of Parkinsonism-Inducing NeurotoxicantsNational Institute Of Environmental Health Sciences2005
- Glutamate In Parkinson'S DiseaseNational Center For Research Resources2004
- A Novel Model Of Parkinson'S DiseaseNational Center For Research Resources2004
- Emory Collaborative Center: PD Environmental ResearchNational Institute Of Environmental Health Sciences2002–2003
- Training In Translational Research In NeurologyNational Institute Of Neurological Disorders And Stroke2000–2003
- Glutamate In Parkinson'S DiseaseNational Institute Of Neurological Disorders And Stroke2000–2003
- New Models Of PD: Pathogenesis And NeuroprotectionNational Institute Of Environmental Health Sciences2002
- Core--Research DevelopmentNational Institute Of Environmental Health Sciences2002
- Excitotoxic--Bioenergetic InteractionsNational Institute On Aging1997–2001
- Glutamate In Parkinsons DiseaseNational Institute Of Neurological Disorders And Stroke1995–1999
- Electron Transport Enzymes In Alzheimers DiseaseNational Institute On Aging1995–1997
- Glutamate In Parkinson'S DiseaseNational Institute Of Neurological Disorders And Stroke1995
- Electron Transport Enzymes In Alzhemiers DiseaseNational Institute On Aging1994–1995
- Mechanisms Of Selective Neuronal VulnerabilityNational Institute Of Neurological Disorders And Stroke1991–1993
- Studies On The Regulation Of Glutamate ReceptorsNational Institute Of Mental Health1985
Professional Memberships
- Member
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