EricHuttonRaabeMD

Pediatric Hematology & Oncology • Baltimore, MD

Pediatric Neuro-Oncology

Associate Professor of Oncology, Instructor of Pathology, Johns Hopkins University School of Medicine

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Office
1800 Orleans Street
Bloomberg 11N
Baltimore, MD 21287
Phone+1 410-955-8751

Summary

I am a board certified pediatric hematologist/oncologist focusing on pediatric brain tumors. In addition to clinical expertise, I lead a research group of post-doctoral fellows, graduate students, and laboratory assistants focused on investigating and disrupting key genetic pathways that drive the most aggressive pediatric brain tumors. We have research interests and on-going collaborations in diffuse intrinsic pontine glioma, glioblastoma, medulloblastoma, atypical teratoid/rhabdoid tumor, and aggressive low grade glioma. The discovery and deployment of new treatments for these high risk brain tumors is the focus of my research and clinical energies.

Education & Training

Johns Hopkins UniversityFellowship, Pediatric Hematology/Oncology, 2007 - 2010
Children's Hospital of PhiladelphiaResidency, Pediatrics, 2003 - 2006
University of Cincinnati College of MedicineClass of 2003
Brown UniversityB.S., Neural Sciences, 1989 - 1993

Certifications & Licensure

MD State Medical License 2007 - 2025
PA State Medical License 2003 - 2024
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013-2014
Francis Schwentker Award for Excellence in Research Pediatrics House Staff and Fellows at Johns Hopkins, 2011
Alpha Omega Alpha University of Cincinnati College of Medicine, 2002
Richard Akeson Travel Award 1999
Nominee, Excellence in Teaching Award for Graduate Assistants 1999
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Clinical Trials

Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG). Start of enrollment: 2013 Mar 08
Completed
Phase 1

Publications & Presentations

PubMed

47 citations
The transcriptional modulator HMGA2 promotes stemness and tumorigenicity in glioblastoma.
Harpreet Kaur, Sabeen Zulfiqar Ali, Lauren Huey, Marianne Hütt-Cabezas, Isabella Taylor
Cancer Letters. 2016-07-10
164 citations
Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer
Francesca Petralia, Nicole Tignor, Boris Reva, Mateusz Koptyra, Shrabanti Chowdhury
Cell. 2020-12-23
2 citations
Systemic Bevacizumab for Recurrent Respiratory Papillomatosis: A Single Institution's Experience.
Raymond J So, Christopher Rayle, Henry H Joo, Emily Y Huang, Tanguy Y Seiwert
The Laryngoscope. 2024-07-01

Journal Articles

Alterations in Cellular Metabolome after Pharmacological Inhibition of Notch in Glioblastoma Cells
Kahlert UD, Cheng M, Koch K, Marchionni L, Fan X, Raabe EH, Maciaczyk J, Glunde K, Eberhart CG, Int J Cancer, 1/30/2015
Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target
Weingart MF, Roth J, Hutt-Cabezas M , Busse T , Kaur H, Price A, Maynard R, Rubens J, Taylor I , Mao XG, Xu J, Kuwahara Y, Allen SJ , Erdreich-Epstein A, Weissman..., Oncotarget, 1/20/2015
The chromatin modifying protein HMGA2 promotes atypical teratoid rhabdoid cell tumorigenicity
Kaur, H, Hutt-Cabezas, M, Weingart, MF, Xu, J, Kuwahara, Y, Erdreich-Epstein, A, Weissman, B, Eberhart, CG, Raabe, EH, J Neuropathol Exp Neurol, 1/1/2015
Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes
Saratsis AM, Kambhampati M, Snyder K, Yadavilli S, Devaney J, Harmon B, Hall J, Raabe EH, An P, Weingart M, Rood BR, Magge S, MacDonald TJ, Packer RJ, Nazarian J, Acta Neuropathol, 1/3/2013
LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumor formation by enacting a pro-invasive genetic program
Mao, XG, Hutt-Cabezas, M, Orr, BA, Weingart, M, Taylor I, Rajan K, Odia Y, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG, Raabe EH, Oncotarget, 1/1/2013
Morphologic characteristics and immunohistochemical profile of diffuse intrinsic pontine gliomas
Ballester LY, Wang Z, Shandilya S, Miettinen M, Burger P, Eberhart CG, Rodriguez F, Raabe E, Warren KE, Quezado M, Am J Surg Pathol, 1/1/2013
BRAF Activation Induces Transformation and then Senescence in Human Neural Stem Cells: A Pilocytic Astrocytoma Model
Raabe, E.H., Lim, K.S., Kim, JM., Meeker, A., Mao, XG., Nikkhah, G., Macizczyk, J., Kahlert, U., Jain, D., Bar, E., Cohen, KJ, Eberhart CG, Clinical Cancer Research, 1/1/2011
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Press Mentions

Combination Drug Therapy for Childhood Brain TumorsApril 7th, 2020
Combination Drug Therapy for Childhood Brain Tumors Shows Promise in Laboratory Models: Researchers Say Findings Support Use in Clinical TrialsFebruary 17th, 2020
Inhibition of mTORC1 in Pediatric Low-Grade Glioma Depletes Glutathione and Therapeutically Synergizes with CarboplatinFebruary 14th, 2020
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Professional Memberships

American Association for Cancer Research - AACR
Member

Other Languages

French

External Links

Johns Hopkins Pediatric Oncologyhttp://www.hopkinsmedicine.org/kimmel_cancer_center/centers/pediatric_oncology/make_a_gift/
Hopkins Medicine http://www.hopkinsmedicine.org/profiles/results/directory/profile/7796842/eric-raabe?CLEARPAGECACHE=false
Eberhart lab pagehttp://apps.pathology.jhu.edu/blogs/eberhart/?page_id=23