EricAKleinMD

PubMed

• 448 citations
  Identification of a Novel Gammaretrovirus in Prostate Tumors of Patients Homozygous for R462Q RNASEL Variant
  Anatoly Urisman, Ross J. Molinaro, Nicole Fischer, Sarah J. Plummer, Graham Casey
  Plos Pathogens. 2006-03-31
• 1414 citations
  Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).
  Scott M. Lippman, Eric A. Klein, Phyllis J. Goodman, M. Scott Lucia, Ian M. Thompson
  JAMA. 2009-01-07
• 15 citations
  Hexose-6-phosphate dehydrogenase blockade reverses prostate cancer drug resistance in xenograft models by glucocorticoid inactivation.
  Jianneng Li, Michael Berk, Mohammad Alyamani, Navin C. Sabharwal, Christopher M Goins
  Science Translational Medicine. 2021-05-26

Journal Articles

• A Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Utility of Tacrolimus (FK506) for the Prevention of Erectile Dysfunction Following Bilateral Nerve-S...  
  John P Mulhall, Eric A Klein, Kevin Slawin, Peter T Scardino, The Journal of Sexual Medicine
• Patient-Level DNA Damage and Repair Pathway Profiles and Prognosis After Prostatectomy for High-Risk Prostate Cancer  
  Evans JR, Zhao SG, Chang SL, Tomlins SA, Erho N, Sboner A, Schiewer MJ, Spratt DE, Kothari V, Klein EA, Den RB, Dicker AP, Karnes RJ, Yu X, Nguyen PL, Rubin MA, de Bon..., JAMA Oncol, 1/7/2016
• Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk  
  Rand KA, Rohland N, Tandon A, Stram A, Sheng X, Do R, Pasaniuc B, Allen A, Quinque D, Mallick S, Le Marchand L, Kaggwa S, Lubwama A; African Ancestry Prostate Cancer G..., Hum Mol Genet, 1/24/2015
• Prostatectomy at high-volume centers improves outcomes and lowers the costs of care for prostate cancer  
  Barzi A, Klein EA, Dorff TB, Quinn DI, Sadeghi S, Prostate Cancer Prostatic Dis, 1/15/2015
• Two susceptibility loci identified for prostate cancer aggressiveness  
  Berndt SI, Wang Z, Yeager M, Alavanja MC, Albanes D, Amundadottir L, Andriole G, Beane Freeman L, Campa D, Cancel-Tassin G, Canzian F, Cornu JN, Cussenot O, Diver WR, ..., Nat Commun, 1/5/2015
• The landscape of prognostic outlier genes in high-risk prostate cancer  
  Zhao SG, Evans JR, Kothari V, Sun G, Larm A, Mondine V, Schaeffer EM, Ross AE, Klein EA, Den RB, Dicker AP, Karnes RJ, Erho N, Nguyen PL, Davicioni E, Feng FY, Clin Cancer Res, 1/2/2015
• Prostate Biopsy Collaborative Group Nonlinear modeling was
applied thoughtfully for risk prediction: the Prostate Biopsy Collaborative Group  
  Nieboer D, Vergouwe Y, Roobol MJ, Ankerst DP, Kattan MW, Vickers AJ, Steyerberg EW, J Clin Epidemiol, 1/1/2015
• Patient-reported quality of life after stereotactic body radiotherapy (SBRT), intensity modulated radiotherapy (IMRT), and brachytherapy  
  Evans JR, Zhao S, Daignault S, Sanda MG, Michalski J, Sandler HM, Kuban DA, Ciezki J, Kaplan ID, Zietman AL, Hembroff L, Feng FY, Suy S, Skolarus TA, McLaughlin PW, We..., Radiother Oncol, 1/1/2015
• Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions  
  Han Y, Hazelett DJ, Wiklund F, Schumacher FR, Stram DO, Berndt SI, Wang Z, Rand KA, Hoover RN, Machiela MJ, Yeager M, Burdette L, Chung CC, Hutchinson A, Yu K, Xu J, T..., Hum Mol Genet, 1/1/2015
• Measuring and predicting prostate cancer related quality of life changes using EPIC for clinical practice  
  Chipman JJ, Sanda MG, Dunn RL, Wei JT, Litwin MS, Crociani CM, Regan MM, Chang P, PROST-QA Consortium, J Urol, 1/1/2014
• A functional variant in NKX31 associated with prostate cancer risk in the Selenium and Vitamin E Cancer Prevention Trial (SELECT)  
  Martinez EE, Darke AK, Tangen CM, Goodman PJ, Fowke JH, Klein EA, Abdulkadir SA, Cancer Prev Res, 1/1/2014
• Adjuvant and salvage radiotherapy after prostatectomy: AUA/ASTRO Guideline  
  Thompson IM, Valicenti RK, Albertsen P, Davis BJ, Goldenberg SL, Hahn C, Klein E, Michalski J, Roach M, Sartor O, Wolf JS Jr, Faraday MM, J Urol, 1/1/2013
• Uncertainty and perception of danger among patients undergoing treatment for prostate cancer  
  Kazer MW, Bailey DE Jr, Chipman J, Psutka SP, Hardy J, Hembroff L, Regan M, Dunn RL, Crociani C, Sanda MG, PROSTQA Consortium Study Group, BJU Int, 1/1/2013
• Multi-institutional prospective evaluation of bowel quality of life after prostate external beam radiation therapy identifies patient and treatment factors associated ...  
  Hamstra DA, Conlon AS, Daignault S, Dunn RL, Sandler HM, Hembroff AL, Zietman AL, Kaplan I, Ciezki J, Kuban DA, Wei JT, Sanda MG, Michalski JM, PROSTQA Consortium Stud..., Int J Radiat Oncol Biol Phys, 1/1/2013
• Prediction of erectile function following treatment for prostate cancer  
  Alemozaffar M, Regan MM, Cooperberg MR, Wei JT, Michalski JM, Sandler HM, Hembroff L, Sadetsky N, Saigal CS, Litwin MS, Klein E, Kibel AS, Hamstra DA, Pisters LL, Kuba..., JAMA, 1/21/2011
• TMPRSS2-ERG gene fusion prevalence and class are significantly different in prostate cancer of Caucasian, African-American and Japanese patients  
  Magi-Galluzzi C, Tsusuki T, Elson P, Simmerman K, LaFargue C, Esgueva R, Klein E, Rubin MA, Zhou M, Prostate, 1/1/2011
• Quality of life and satisfaction with outcome among prostate-cancer survivors  
  Sanda MG, Dunn RL, Michalski J, Sandler HM, Northouse L, Hembroff L, Lin X, Greenfield TK, Litwin MS, Saigal CS, Mahadevan A, Klein E, Kibel A, Pisters LL, Kuban D, Ka..., N Engl J Med, 1/1/2008
• Natural history of biochemical recurrence after radical prostatectomy: risk assessment for secondary therapy  
  Simmons M, Stephenson AJ, Klein EA, Eur Urology, 1/1/2007
• Genetic susceptibility and oxidative stress in prostate cancer: an integrated model with implications for prevention  
  Klein EA, Casey G, Silverman RH, Urology, 1/1/2006
• Chemoprevention of prostate cancer  
  Thompson IM, Goodman PA, Tangen CM, Leach RJ, Canby-Higano E, Klein EA, Lippman SM, Grand Rounds in Urology, 1/1/2005
• Chemoprevention of prostate cancer  
  Klein EA, Critical Reviews in Oncology/Hematology, 1/1/2005
• Management of Localized Prostate Cancer in ProstateCancer Foundation’s Report to the Nation on Prostate Cancer  
  Klein EA, Roach M, Medscape, 1/1/2004
• Update on Chemoprevention in Prostate Cancer  
  Klein EA, Thompson IM, Current Opinion in Urology, 1/1/2004
• Clinical models for testing chemopreventive agents in prostate cancer and overview of SELECT: the Selenium and Vitamin E Cancer Prevention Trial  
  Klein EA, Recent Results Cancer Res, 1/1/2003
• Challenges and opportunities to the design and implementation of chemoprevention trials for prostate cancer  
  Thompson IM, Basler JA, leach R, Troyer D, Klein E, Brawley O, Urol Oncol, 1/1/2003
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Books/Book Chapters

• Campbell-Walsh Urology 
  Chapter: Epidemiology, Etiology, and Prevention of Prostate Cancer 
  Stephenson AJ, Klein EAEditors: Alan J. Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA.WB Saunders, Philadelphia, PAEdition 11th,2015
• Epidemiology, Etiology, and Prevention of Prostate Cancer in Campbell-Walsh Urology 
  Abouassaly R, Thompson I, Platz E, Klein EAEditors: Alan J. Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA.WB Saunders, Philadelphia, PAEdition 10th,2012
• The Management of Prostate Cancer 
  Klein EA, Jones JSHumana Press, Totowa, NJEdition 3rd,2012
• Organ Specific Cancer Control: Prostate Cancer. ASCO Curriculum: Cancer Prevention 
  Klein EAAmerican Society of Clinical Oncology, Alexandria, VA2007
• Operative Urology at the Cleveland Clinic 
  Chapter: Radical Retropubic Prostatectomy 
  Klein EAEditors: Novick AC, Jones JS, Gill IS, Klein EA, Rackley R, Ross JH.Humana Press, Totowa, NJ2006
• Operative Urology at the Cleveland Clinic 
  Chapter: Radical Cystectomy and Orthotopic Diversion in Men and Women 
  Klein EAEditors: Novick AC, Jones JS, Gill IS, Klein EA, Rackley R, Ross JH.Humana Press, Totowa, NJ2006
• Operative Urology at the Cleveland Clinic 
  Chapter: Nerve-Sparing Retroperitoneal Lymphadenectomy 
  Klein EAEditors: Novick AC, Jones JS, Gill IS, Klein EA, Rackley R, Ross JH.Humana Press, Totowa, NJ2006
• Campbell-Walsh Urology 
  Chapter: Epidemiology, Etiology, and Prevention of Prostate Cancer 
  Klein EA, Platz EA, Thompson IMEditors: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA.WB Saunders, Philadelphia, PAEdition 9th,2006
• Prostate Cancer: Principles and Practice 
  Chapter: Chemoprevention of Prostate Cancer: Concepts and Evidence 
  Klein EAEditors: Kirby RS, Partin AW, Feneley M, Parsons JK.Taylor and Francis, New York, NY2005
• The Management of Prostate Cancer 
  Chapter: Contemporary technique of radical prostatectomy: Open Approach 
  Klein EAEditors: Klein EA.Humana Press, Totowa, NJEdition 2nd,2004
• Clinical Preventive Medicine 
  Chapter: Prostate Cancer 
  Klein EAEditors: RS Lang and DD Hansrud.AMA Press, Chicago, ILEdition 2nd,2004
• The Management of Prostate Cancer 
  Chapter: Counseling patients with localized prostate cancer: radiation or surgery? 
  Klein EA and Kupelian PAEditors: Klein EA.Humana Press, Totowa, NJEdition 2nd,2004
• Vitamin E and Health 
  Chapter: Selenium and Vitamin E Cancer Prevention Trial 
  Klein EAEditors: Kelly F Meydani M, Packer L.Ann NY Acad Sci, New York, NY2004
• So You're Having Prostate Surgery? 
  Klein EA, Jamnicky L, Nam RJohn Wiley and Sons, Hoboken, NJ2004
• Tumor Prevention and Genetics 
  Chapter: Clinical models for testing chemopreventive agents in prostate cancer and overview of SELECT: The Selenium and Vitamin E Cancer Prevention Trial 
  Klein EAEditors: H-J Senn and R. Morant.Springer-Verlag, Berlin, Germany2003
• Screening for Prostate Cancer 
  Chapter: The use of PSA and its derivatives for screening 
  Jhaveri FM, Brawer M, Klein EAEditors: Thompson IM, Klein EA, and Resnick MI.Humana Press, Totowa, NJ2001
• Prostate Cancer 
  Chapter: Management of newly diagnosed metastatic prostate cancer 
  Boccon-Gibod L, Bruchovsky N, Crawford ED, Iverson P, Kirk D, Kittamura T, Klein E, Labrie F, McConnell J, McKiel C, Vargas REditors: Murphy G, Khoury S, Partin A, Denis L.Health Publication Ltd, Plymouth, UKEdition 2nd,2000
• Office Urology 
  Chapter: Selecting and counseling patients on appropriate treatment of prostate cancer 
  Jhaveri FM, Klein EAEditors: Kursh E and Ulchaker J.Humana Press, Totowa, NJ2000
• Advanced Therapy in Prostatic Disease 
  Chapter: Continence-enhancing techniques in radical prostatectomy 
  Licht MR, Klein EAEditors: Resnick MR and Thomson I.BC Decker, Inc, Hamilton, ONT2000
• Comprehensive Textbook of Genitourinary Oncology 
  Chapter: Adrenal Neoplasms 
  Bukowski R, Klein EAEditors: N. Vogelzang, PT Scardino, WV Shipley, DS Coffey.Williams and Wilkins, Philadelphia, PAEdition 2nd,2000
• The Management of Prostate Cancer 
  Chapter: Contemporary technique of radical retropubic prostatectomy 
  Klein EA, Licht MR, Jhaveri FMEditors: Klein EA.Humana Press, Totowa, NJ2000
• Five-Minute Urology Consult 
  Chapter: Adult polycystic kidney disease 
  Liou L, Klein EAEditors: Gomella and M. Dambro.Williams and Wilkins, Baltimore, MD2000
• Five-Minute Urology Consult 
  Chapter: Adrenal medullary neuroblastoma 
  Hsu THS, Ross J and Klein EAEditors: L. Gomella and M. Dambro.Williams and Wilkins, Baltimore, MD2000
• Regional Chemotherapy: clinical research and practice 
  Chapter: Intravesical therapy for superficial bladder cancer 
  Kilbridge KL and Klein EAEditors: M Markman.Humana Press, Totowa, NJ2000
• Urologic Oncology 
  Chapter: Nongerm cell tumors of the testis 
  Klein EA and Levin HSEditors: JE Oesterling and J Richie.WB Saunders, Philadelphia, PA1997
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Lectures

• Development of a comprehensive cell-free DNA (cfDNA) assay for early detection of multiple tumor types: The Circulating Cell-free Genome Atlas (CCGA) study. 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/4/2018
• Biomarkers in Prostate Cancer 
  1/30/2014
• Prostate Cancer: Past, Present, and Future Perfect. The Dawn of the Precision Medicine Era 
  1/2/2014
• OUS 2013 Annual Meeting 
  Ohio Urological Society, Sandusky, Ohio - 3/15/2013
• The Selenium and Vitamin E Cancer Prevention Trial: Lessons Learned 
  University of Toronto - 1/24/2009
• Prostate Cancer Detection and Risk Stratification 
  Brown University - 1/3/2009
• Viral Etiology of Prostate Cancer 
  University of Toronto - 1/12/2007
• Is Prostate Cancer a Viral Disease? 
  Cedars-Sinai Medical Center, Los Angeles, CA - 1/4/2007
• Is Prostate Cancer an Infectious Disease? 
  1/6/2006
• Radiation and Surgery in the Management of Localized Prostate Cancer 
  Medical College of Georgia - 1/2/2005
• Chemoprevention and Genetics of Prostate Cancer 
  University of Wisconsin Comprehensive Cancer Center - 1/10/2003
• Localized Prostate Cancer: Radiation or Surgery? 
  Washington University in St. Louis, MO - 1/23/2001
• Contemporary Management of Prostate Cancer 
  St. Joseph Mercy Medical Center, Ann Arbor, MI - 1/15/2000
• Current Trends in the Management of Prostate Cancer 
  Shadyside Hospital, Pittsburgh, PA - 1/21/1996
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Other

• Initial approach to low-risk clinically localized prostate cancer 
  Klein EA
  http://www.uptodate.com/contents/initial-approach-to-low-risk-clinically-localized-prostate-cancer
  UpToDate, Wolters Kluwer Health - 2013-02-05
• Prostate cancer: Risk stratification, other prognostic factors, and predictive tools 
  Klein EA
  http://www.uptodate.com/contents/prostate-cancer-risk-stratification-other-prognostic-factors-and-pr
  UpToDate, Wolters Kluwer Health - 2012-07-06
• Radical prostatectomy for localized prostate cancer 
  Klein EA
  http://www.uptodate.com/contents/radical-prostatectomy-for-localized-prostate-cancer
  UpToDate, Wolters Kluwer Health - 2013-01-03
• Prostate cancer treatment; stage I to III cancer 
  Klein EA
  http://www.uptodate.com/contents/prostate-cancer-treatment-stage-i-to-iii-cancer-beyond-the-basics
  UpToDate, Wolters Kluwer Health - 2011-10-06
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