DonaldWNorthfeltMD

PubMed

• 72 citations
  Enrichment of PI3K-AKT-mTOR Pathway Activation in Hepatic Metastases from Breast Cancer.
  Mariaelena Pierobon, Corinne Ramos, Shukmei Wong, K. Alex Hodge, Jessica Aldrich
  Clinical Cancer Research. 2017-08-15
• 118 citations
  Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Can...
  Douglas Yee, Angela DeMichele, Christina Yau, Claudine Isaacs, W. Fraser Symmans
  JAMA Oncology. 2020-09-01
• 10 citations
  A randomized phase 2 study of neoadjuvant carboplatin and paclitaxel with or without atezolizumab in triple negative breast cancer (TNBC) - NCI 10013.
  Foluso O Ademuyiwa, Feng Gao, Cherease R Street, Ina Chen, Donald W Northfelt
  NPJ Breast Cancer. 2022-12-30

Journal Articles

• Phase 2 Trial of Paclitaxel Polyglumex with Capecitabine for Metastatic Breast Cancer  
  Northfelt DW, Allred JB, Liu HS, Hobday TJ, Rodacker MW, Lyss AP, Fitch TR, Perez EA, American Journal Of Clinical Oncology-cancer Clinical Trials, 1/1/2014
• Clinical Utility of Gene Expression Profiling Data for Clinical Decision-Making regarding Adjuvant Therapy in Early Stage, Node-Negative Breast Cancer: A Case Report  
  Schuster SR, Pockaj BA, Bothe MR, David PS, Northfelt DW, J Pers Med, 1/1/2012
• Osteoporosis Prevention in Prostate Cancer Patients Receiving Androgen Ablation Therapy: Placebo-controlled Double-blind Study of Estradiol and Risedronate: N01C8  
  Kearns AE, Northfelt DW, Dueck AC, Atherton PJ, Dakhil SR, Rowland KM Jr, Fuloria J, Flynn PJ, Dentchev T, Loprinzi CL, Support Care Cancer, 1/1/2010
• Patients Seeking Second Medical Hematology/oncology Opinions in the United States: A Report of Their Demographics and Disease Processes  
  Curtis KK, Northfelt DW, Community Oncol, 1/1/2007
• Incorporating Genetic Counseling into Primary Care Practice  
  Hunt KS, Northfelt DW, Resident & Staff Physician, 1/1/2006
• Management of Severe Gastrointestinal Bleeding in a Patient with Acquired Von Willebrand Disease Complicating Enteropathic-associated T-cell Lymphoma  
  Campbell NE, Garvey PB, Northfelt DW, Leighton JA, Heppell JP, Pract Gastroenterol, 1/1/2006
• Chemotherapy Error: Practical Approaches to Increasing Patient Safety  
  Harris TJ, Northfelt DW, J Patient Safety, 1/1/2005
• A Dose- and Schedule-finding Study of Darbepoetin Alpha for the Treatment of Chronic Anaemia of Cancer  
  Smith RE, Tchekmedyian NS, Chan D, Meza LA, Northfelt DW, Patel R, Austin M, Colowick AB, Rossi G, Glaspy J, Br J Cancer, 1/16/2003
• Pegylated-liposomal Doxorubicin versus Doxorubicin, Bleomycin, and Vincristine in the Treatment of AIDS-related Kaposi's Sarcoma: Results of a Randomized Phase III Cli...  
  Northfelt DW, Dezube BJ, Thommes JA, Miller BJ, Fischl MA, Friedman-Kien A, Kaplan LD, DuMond C, Mamelok RD, Henry DH, Classic Papers and Current Comments, 1/1/2002
• Editorial Comment: The Spectrum and Complexity of HIV-related Cancers  
  Northfelt DW, The AIDS Reader, 1/1/1998
• Liposome-encapsulated Anthracycline Chemotherapy for AIDS-related Kaposi's Sarcoma  
  Northfelt DW, The AIDS Reader, 1/1/1997
• Liposomal Anthracycline Chemotherapy in the Treatment of AIDS-related Kaposi's Sarcoma  
  Northfelt DW, Oncology, 1/1/1997
• Human Papillomavirus-associated Malignancies  
  Northfelt DW, Opportunistic Complications of HIV, 1/1/1996
• Clinicopathologic Conference: Gingival Mass Lesions in a Patient with HIV Infection  
  Gowdey G, Lipsey LR, Lee R, Jacques C, Northfelt DW, Oral Surg Oral Med Oral Pathol, 1/1/1995
• AIDS-related Kaposi's Sarcoma: Still a Problem, Still an Opportunity  
  Northfelt DW, J Clin Oncol, 1/1/1994
• Mycobacterium Avium Complex Infection in AIDS: Clinical Presentation, Diagnosis, and Current Therapy  
  Northfelt DW, The AIDS Reader, 1/1/1993
• When AIDS Patients Get Cancer  
  Duvic M, Kaplan LD, Northfelt DW, Siegel BJ, Patient Care, 1/1/1993
• Rationale for Early Antiviral Therapy for HIV Infection  
  Northfelt DW, Volberding PA, HIV: Advances in Research and Therapy, 1/1/1992
• AIDS-related Kaposi's Sarcoma  
  Northfelt DW, AIDSFILE, 1/1/1992
• The Changing Face of AIDS: The Emerging Malignancies  
  Northfelt DW, Current Opinion in Infectious Disease, 1/1/1991
• AIDS-Associated Non-Hodgkin's Lymphoma  
  Northfelt DW, Kaplan LD, Current Opinion in Oncology, 1/1/1991
• Lung Cancer in Persons with Human Immunodeficiency Virus Infection  
  Northfelt DW, Jacobson MA, J Respir Dis, 1/1/1991
• Combination Antiretroviral Therapy for HIV Infection  
  Northfelt DW, AIDSFILE, 1/1/1991
• Extrapulmonary Pneumocystosis  
  Northfelt DW, AIDS Medical Report, 1/1/1991
• Human Papillomavirus-associated Malignancy in Patients with HIV Infection  
  Northfelt DW, AIDS Medical Report, 1/1/1991
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Books/Book Chapters

• HIV InSite Knowlege Base 
  Chapter: Other Malignancies Associated with HIV 
  Northfelt DW2003
• The Medical Management of AIDS 
  Chapter: Malignancies Associated with AIDS 
  Page 467 - 496Kaplan LD, Northfelt DWEditors: Sande MA, Volberding PA.W.B. Saunders Co., PhiladelphiaEdition 6th,1999
• The AIDS Knowledge Base 
  Chapter: Hematologic Aspects of HIV Infection 
  Page 505 - 514Northfelt DWEditors: Cohen PT, Sande MA, Volberding PA.Lippincott Williams & Wilkins, PhiladelphiaEdition 3rd,1999
• The AIDS Knowledge Base 
  Chapter: Other Neoplasms Associated with HIV 
  Page 857 - 859Northfelt DWEditors: Cohen PT, Sande MA, Volberding PA.Lippincott Williams & Wilkins, PhiladelphiaEdition 3rd,1999
• HIV InSite Knowlege Base 
  Chapter: Hematologic manifestations of HIV 
  Northfelt DW1998
• Long Circulating Liposomes: Old Drugs, New Therapeutics 
  Chapter: Pegylated-liposomal Doxorubicin (Doxil) In the Treatment of AIDS-related Kaposi's Sarcoma 
  Page 127 - 141Northfelt DWEditors: Storm G, Woodle M.Landes Bioscience, Georgetown1998
• Pocketguide on Cancer Chemotherapy 
  Chapter: Pain Management of the Cancer Patient 
  Page 385 - 401Harney E, Northfelt DEditors: Ignoffo RJ, Viele C, Venook A, Damon L.Lippincott-Raven Publishing Co., Philadelphia1998
• Management of the HIV-infected Patient 
  Chapter: Neoplasia and HIV Infection 
  Page 366 - 383Kaplan L, Northfelt DEditors: Crowe S, Hoy J, Mills J.Cambridge University Press, Cambridge1996
• Stealth liposomes 
  Chapter: Pharmacokinetics and Tumor Localization of DOX-SL (Stealth Liposomal Doxorubicin) By Comparison with Adriamycin in Patients with AIDS and Kaposi's Sarcoma 
  Page 257 - 266Northfelt DW, Kaplan L, Russell J, Volberding PA, Martin FJ.Editors: Lasic D, Martin F.CRC Press, Inc., Boca Raton1995
• The AIDS Knowledge Base 
  Chapter: Clinical Manifestations of HIV Infection: Hematologic Aspects 
  Northfelt DWEditors: Cohen PT, Sande MA, Volberding PA.Little, Brown and Co., Boston1994
• The AIDS Knowledge Base 
  Chapter: Kaposi's Sarcoma: Epidemiology 
  Northfelt DWEditors: Cohen PT, Sande MA, Volberding PA.Little, Brown and Co., Boston1994
• The AIDS Knowledge Base 
  Chapter: Cervical Neoplasia 
  Northfelt DWEditors: Cohen PT, Sande MA, Volberding PA.Little, Brown and Co., Boston1994
• The AIDS Knowledge Base 
  Chapter: Anal Neoplasia 
  Northfelt DWEditors: Cohen PT, Sande MA, Volberding PA.Little, Brown and Co., Boston1994
• The AIDS Knowledge Base 
  Chapter: Other Malignancies 
  Northfelt DWEditors: Cohen PT, Sande MA, Volberding PA.Little, Brown and Co., Boston1994
• AIDS: Etiology, Diagnosis, Treatment, and Prevention 
  Chapter: Hematologic Complications of HIV Infection 
  Page 337 - 345Northfelt DW, Mitsuyasu RTEditors: DeVita VT, Hellman S, Rosenberg SA.JB Lippincott, PhiladelphiaEdition 3rd,1992
• The Medical Management of AIDS 
  Chapter: The Malignancies Associated with AIDS 
  Page 399 - 429Kaplan LD, Northfelt DWEditors: Sande MA, Volberding PA.W.B. Saunders Co., PhiladelphiaEdition 3rd,1992
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Abstracts/Posters

• A Phase I/ii Dose Escalation Study of Tkm-080301, a Rnai Therapeutic Directed against Plk1, in Patients with Advanced Solid Tumors, with an Expansion Cohort of Patient...
  Ramanathan RK, Hamburg SI, Halfdanarson TR, Borad MJ, Seetharam M, Curtis KK, Lee P, Fredlund P, Gilbert M, Semple SC, Judge AD, Crowell B, Vocila L, MacLachlan I, Nor..., Pancreas, 1/1/2014
• Back to Basics: Traditional Nottingham Grade Mitotic Scores Alone Are Significant in Predicting Survival
  McCullough A, Dueck A, Ocal T, Lidner T, Gray R, Nabil W, Northfelt D, Anderson K, Pockaj B, Ann Surg Oncol, 1/1/2014
• Phase I Dose-escalation And Drug Interaction Study Of Abt-888 (parp1 Inhibitor) And Topotecan (topoisomerase I Inhibitor) In Patients With Advanced Cancer
  Boakye-Agyeman F, Reid J, Menefee M, Buhrow S, Walden C, Piens J, Kayode O, Erlichman C, Haluska P,Northfelt DW, Kaufmann SH, Ames M, Satele DV, Tang H, Peethambaram P..., Clin Pharmacol Ther, 1/1/2014
• Transcriptome-wide Association of Mki67 Expression: Pre- And Post-neoadjuvant Paclitaxel
  Moyer AM, Kalari KR, Thompson KJ, Visscher DW, Suman VJ, Eckel-Passow J, Sicotte H, Hart SN, Sinnwell JP, Dockter TJ, Jones KN, Conners AL, Tang X, Yu J, Gao B, Mahone..., Mod Pathol, 1/1/2014
• Transcriptome-wide Association of Mki67 Expression: Pre- And Post-neoadjuvant Paclitaxel
  Moyer AM, Kalari KR, Thompson KJ, Visscher DW, Suman VJ, Eckel-Passow J, Sicotte H, Hart SN, Sinnwell JP, Dockter TJ, Jones KN, Conners AL, Tang X, Yu J, Gao B, Mahone..., Lab Invest, 1/1/2014
• A Phase I Dose Escalation Study of Tkm-080301, a Rnai Therapeutic Directed against Plk1, in Patients with Advanced Solid Tumors
  Ramanathan RK, Hamburg SI, Borad MJ, Seetharam M, Kundranda MN, Lee P, Fredlund P, Gilbert M, Mast C, Semple SC, Judge AD, Crowell B, Vocila L, MacLachlan I, Northfelt DW, Cancer Res, 1/15/2013
• Combination Trastuzumab and Chemotherapy To Induce Immunity to Multiple Tumor Antigens in Patients with HER2-positive Metastatic Breast Cancer: NCCTG (Alliance) Studie...
  Clynes R, Knutson KL, Ballman KV, Erskine CL, Norton N, Sumrall SV, Northfelt DW, Tan W, Calfa CJ, Pegram MD, Perez EA, J Clin Oncol, 1/1/2013
• A Prospective Evaluation of Cyp2d6 Enzyme Activity Using Adextromethorphan Breath Test (Dm-bt) In Women Receiving Adjuvant Tamoxifen (Tam)
  Reid JM, Suman VJ, Northfelt DW, Rosen DI, Safgren SL, Gilbert JA, Kosel ML, Modak AS, Ames MM, Goetz MP, Clin Pharmacol Ther, 1/1/2013
• N0321: A Phase II Study of Bortezomib, Paclitaxel, Carboplatin, and Radiotherapy for Locally Advanced Non-small Cell Lung Cancer
  Schild SE, Molina JR, Dy GK, Rowland KM, Sarkaria JN, Thomas SP, Northfelt DW, Kugler JW, Foster NR, Adjei AA, J Clin Oncol, 1/1/2012
• A Phase 1 Study of Medi-573, an Investigational Monoclonal Antibody That Targets IGF-I and IGF-II: Safety, Pharmacokinetics, and Antitumor Activity in Adults with Adva...
  Haluska P, Menefee ME, Plimack ER, Rosenberg JE, Northfelt DW, LaVallee T, Huang W, Yu XQ, Viner JL, LoRusso P, Eur J Cancer, 1/1/2012
• Pharmacogenomics of Breast Cancer Endocrine Therapy: Tsply5 Snps Are Associated with Plasma Estradiol (E2) Concentrations and the Regulation of Aromatase
  Liu M, Wang L, Fridley BL, Buzdar A, Robson ME, Kubo M, Batzler A, Jenkins GD, Pietrzak TL, Goetz MP, Northfelt DW, Perez EA, Williard CV, Schaid DJ, Nakamura Y, Ingle..., Clin Pharmacol Ther, 1/1/2012
• Phase I Study of Panobinostat (LBH489) And Letrozole in Postmenopausal Women with Metastatic Breast Cancer
  Tan W, Allred JB, Moreno-Aspitia A, Northfelt DW, Ingle JN, Perez EA, J Clin Oncol, 2012 ASCO Annual Meeting Proceedings, 1/1/2012
• Phase I Trial of a Novel Combination of An HDAC Inhibitor (LBH589) And an mTOR Inhibitor (RAD001) In Lymphoid and Plasma Cell Malignancies
  Kumar S, Mikhael JR, LaPlant BR, Colgan JP, Inwards DJ, Johnston PB, Laumann K, Micallef IN, Nowakowski GS, Ansell SM, Curtis K, Dispenzieri A, Lacy MQ, Leis JF, North..., Blood, 1/18/2011
• NCCTG Phase II Trial of Bevacizumab in Combination with Sorafenib (BEV/SOR) In Recurrent Glioblastoma (RGBM)
  Galanis E, Anderson SK, Lafky JM, Kaufmann TJ, Uhm JH, Giannini C, Kumar SK, Northfelt DW, Flynn PJ, Jaeckle KA, Buckner JC, Neuro-oncol, 1/1/2011
• Improved Outcome in Recurrent Glioblastoma (RGBM) Patients Treated With Bevacizumab (BEV) And Sorafenib (SOR) Is Predicted by a Greater Drop in Apparent Diffusion Coef...
  Kaufmann TJ, Anderson SK, Jaeckle KA, Uhm JH, Northfelt DW, Flynn PJ, Buckner JC, Galanis E, Neuro-oncol, 1/1/2011
• First-in-man Phase I Clinical Trial of VTX-2337-a Selective Toll-like Receptor 8 (TLR8) Agonist - In Oncology Patients
  Northfelt D, Ramanathan R, Cohen P, Von Hoff, Manjarrez K, Dietsch G, Hershberg R, J Immunother, 1/1/2011
• Phase II Trial Combining Nab-paclitaxel (NP), Gemcitabine (G) And Bevacizumab (B) In Patients (Pts) With Metastatic Breast Cancer (MBC): NCCTG N0735
  Northfelt DW, Dueck AC, Flynn TP, Stella PJ, Zander PJ, Melnik MK, Pavey ES, Perez EA, J Clin Oncol, 1/1/2011
• Genetic Associations with Taxane-induced Neuropathy by Genome Wide Association Study (GWAS) In E5103
  Schneider BP, LI L, Miller K, Flockhart D, Radovich M, Hancock BA, Kassem N, Foroud T, Koller DL, Badve SS, Li Z, Patridge AH, O'Neill AM, Sparano JA, Dang CT, Northfe..., J Clin Oncol, 1/1/2011
• Clinical Characteristics, Univariate, and Multivariate Cox Model Analysis of Long-term (> 3 Years) Survivors of Stage IV Metastatic Breast Cancer Treated on Phase I...
  Patel TA, Liu H, Hillman DW, Dueck AC, Ingle JN, Roy V, Hobday TJ, Northfelt DW, Perez EA, North Central, J Clin Oncol, 1/20/2010
• Clinical Pharmacokinetics and Pharmacodynamics of CX-4945, a Novel Inhibitor of Protein Kinase CK2: Interim Report from the Phase I Clinical Trial
  Northfelt DW, 22nd EORTC-NCI-AACR Symposium on "Molecular Targets and Cancer Therapeutics", Berlin, Germany, 1/1/2010
• Clinical Pharmacokinetics and Pharmacodynamics of CX-4945, a Novel Inhibitor of Protein Kinase CK2: Interim Report from the Phase 1 Clinical Trial
  Padgett CS, Lim JKC, Marschke RF, Northfelt DW, Andreopoulou E, Von Hoff, Anderes K, Ryckman DM, Chen TK, O'Brien SE, Ejc Supplements, 1/1/2010
• Increase in Contralateral Prophylactic Mastectomy-echoes of a Bygone Era?
  Stucky CC, Dueck A, Gray R, Wasif N, Northfelt D, McLaughlin S, Pockaj B, Ann Surg Oncol, 1/1/2010
• Obese Patients Present with More Advanced Cancers: The Impact of Obesity on Breast Cancer
  Haakinson D, Stucky CC, Dueck A, Gray R, Wasif N, Northfelt D, Apsey H, Pockaj B, Ann Surg Oncol, 1/1/2010
• Triple-negative Breast Cancers: Unique Clinical Presentations and Outcomes
  Yee J, Dueck A, Stucky CC, Gray R, Wasif N, Northfelt D, McCullough A, Pockaj B, Ann Surg Oncol, 1/1/2010
• A Phase 1b Clinical Trial of Dacetuzumab in Combination With Rituximab and Gemcitabine: Multiple Responses Observed in Patients with Relapsed Diffuse Large B-cell Lymp...
  Forero-Torres A, Bartlett NL, Nasta SD, Northfelt D, Beaven A, Myint H, Whiting NC, Drachman JG, Moskowitz CH, Blood, 1/20/2009
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Lectures

• Interesting Cases in Breast Disease 
  Scottsdale, Arizona - 1/1/2013
• What's New in Breast, Lung, Prostate, and Colon Cancer for the Primary Physician 
  Sedona, Arizona - 1/1/2012
• What Should I Eat, How Should I Exercise, How Can I Lose Weight? 
  Scottsdale, Arizona - 1/1/2012
• Utility of Clinical Biomarkers for Detecting Protein Kinase CS2 Inhibition: A Report from the Phase I Trial of CX-4945 
  Chicago, Illinois - 1/1/2010
• Genomics in Everyday Medical Practice 
  Mayo Clinic Arizona Scottsdale, Arizona - 1/1/2009
• Genomics Drives 21st Century Breast Cancer Care 
  Scottsdale, Arizona - 1/1/2009
• Anemia for the Primary Care Physician 
  1/1/2009
• Genetic Predictive Markers for Hormonal and Chemotherapy Decisions in the Adjuvant Setting 
  Jacksonville, Florida - 1/1/2009
• Adjuvant Chemotherapy: Standard Recommendations and New Trials 
  1/1/2008
• Individualized Medicine: The Future 
  1/1/2008
• A Phase Ib/II Study of PXD101 Alone and in Combination with 5-fluorouracil in Patients with Advanced Solid Tumors 
  Chicago, Illinois - 1/1/2007
• Individualized Medicine 
  Mayo Clinic Arizona Scottsdale, Arizona - 1/1/2007
• Chemotherapy for Lung Cancer 
  Mayo Clinic Jacksonville Jacksonville, Florida - 1/1/2007
• Cancer: Preoperative Management 
  Mayo Clinic Arizona Scottsdale, Arizona - 1/1/2007
• Common Complications of Breast Cancer Therapy and What You Can do About Them: Chemotherapy/Hormonal Therapy 
  Mayo Clinic Arizona Scottsdale, Arizona - 1/1/2007
• Hormone Replacement Therapy for High Risk and Breast Cancer Patients - What is the Evidence? 
  Mayo Clinic Arizona Scottsdale, Arizona - 1/1/2007
• Therapeutic Considerations 
  Mayo Clinic Arizona Scottsdale, Arizona - 1/1/2007
• Stem Cell Therapy 
  Mayo Clinic Arizona - 1/1/2006
• Breast Cancer/Genomics Update 
  Fountain Hills, Arizona - 1/1/2006
• The Multiple Phases of Kaposi's Sarcoma: Is There a 'Best Treatment' 
  Comprehensive Cancer Center, Desert Regional Medical Center Palm Springs, California - 1/1/2006
• Kaposi's Sarcoma, AIDS and Cancer 
  St. Vincent's Comprehensive Cancer Center New York, New York - 1/1/2006
• Adjuvant Therapy of Breast Cancer 
  Mayo Clinic Jacksonville Jacksonville, Florida - 1/1/2006
• Breast Cancer Genomics 
  Mayo Clinic Jacksonville Jacksonville, Florida - 1/1/2006
• Genomics in Primary Care 
  Mayo Clinic Arizona Sedona, Arizona - 1/1/2005
• Lung Cancer Screening 
  Mayo Clinic Arizona Sedona, Arizona - 1/1/2005
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Other

• Breast Cancer Research: A Leap Ahead 
  Northfelt D, American Cancer Society Video
  1/1/2001