DavidDTranMDPhD

Neuro-Oncology

Co-Director, USC Brain Tumor Center Chief, Neuro-Oncology Professor of Neurosurgery and Neurology University of Southern California Keck School of Medicine

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Office
1520 San Pablo St
Ste 3800
Los Angeles, CA 90033
Phone+1 323-442-5720

Clinical Expertise

Neuro-oncology, Tumor immunotherapy, Biomedical research

Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Hematology and Medical Oncology, 2007 - 2011
Washington University/B-JH/SLCH ConsortiumResidency, Internal Medicine, 2005 - 2007
Mayo Clinic College of MedicineClass of 2005
Mayo Clinic College of MedicinePhD, Biomedical Sciences, 2003

Certifications & Licensure

CA State Medical License 2023 - 2025
FL State Medical License 2015 - 2023
MO State Medical License 2007 - 2016
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2012

Clinical Trials

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer Start of enrollment: 2006 Dec 01
Active, not recruiting
Phase 3
Concentration and Activity of Lapatinib in Vestibular Schwannomas Start of enrollment: 2009 Jun 01
Completed
Early Phase 1
Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM) Start of enrollment: 2009 Jun 01
Completed
Phase 3
Post-approval Study of NovoTTF-100A in Recurrent GBM Patients Start of enrollment: 2012 Dec 01
Terminated
Phase 4
Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma Start of enrollment: 2013 Jun 01
Completed
Phase 3
Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery Start of enrollment: 2013 May 01
Terminated
Phase 2
MRI-Guided Laser Surgery and Doxorubicin Hydrochloride in Treating Patients With Recurrent Glioblastoma Multiforme Start of enrollment: 2013 Aug 13
Completed
Phase 1
TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma Start of enrollment: 2016 Dec 19
Terminated
Phase 2
FORWARD Optune and Adjuvant TMZ in Grade II/III Astrocytoma Start of enrollment: 2019 May 20
Terminated
Phase 2
A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER) Start of enrollment: 2020 Sep 26
Recruiting
Phase 1, Phase 2
Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP) Start of enrollment: 2018 Feb 23
Active, not recruiting
Phase 2
MK-3475 in Combination With MRI-guided Laser Ablation in Recurrent Malignant Gliomas Start of enrollment: 2015 Aug 05
Completed
Phase 1, Phase 2
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Publications & Presentations

PubMed

169 citations
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A P...
Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim
JAMA Oncology. 2023-01-01
393 citations
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.
Eugenia Trushina, Roy B. Dyer, John D. Badger, Daren R. Ure, Lars Eide
Molecular and Cellular Biology. 2004-09-15
89 citations
An NAD+-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma
Amit D. Gujar, Son Le, Diane D. Mao, David Y. A. Dadey, Alice Turski
Proceedings of the National Academy of Sciences of the United States of America. 2016-12-20

Press Mentions

Zai Lab Announces First Quarter 2022 Financial Results and Corporate UpdatesMay 11th, 2022
Updated 2-THE-TOP Data Suggest Improvements in Progression-Free Survival, Overall Survival Compared to Matched-Control Patients from EF-14 TrialMarch 24th, 2022
Study Shows TTFields Holds Promise to Potentially Trigger Immune Response Against GBM RecurrenceFebruary 25th, 2022
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