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David Kastenberg, MD, Gastroenterology, Philadelphia, PA

DavidM.KastenbergMD

Gastroenterology Philadelphia, PA

Gastrointestinal Cancer, Inflammatory Bowel Disease

The J. Edward Berk Professor of Medicine, Chief, Division of Gastroenterology & Hepatology Enterprise Director, Gastroenterology, Thomas Jefferson University, Sidney Kimmel Medical College

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  • Office

    1101 Chestnut St
    Philadelphia, PA 19107
    Phone+1 215-955-8900
    Fax+1 215-955-5245

Education & Training

  • Sidney Kimmel Medical College at Thomas Jefferson University/TJUH
    Sidney Kimmel Medical College at Thomas Jefferson University/TJUHFellowship, Gastroenterology, 1990 - 1992
  • Temple University Hospital
    Temple University HospitalResidency, Internal Medicine, 1987 - 1990
  • New York University School of Medicine
    New York University School of MedicineClass of 1987

Certifications & Licensure

  • NJ State Medical License
    NJ State Medical License 1995 - 2025
  • PA State Medical License
    PA State Medical License 1990 - 2024
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Gastroenterology

Awards, Honors, & Recognition

  • Top Doctor Philadelphia Magazine, 2010-2023
  • America's Top Doctors for Cancer (Discontinued 2021) Castle Connolly, 2016-2021
  • Top Doctor Philadelphia Magazine, South Jersey Magazine, 2010-2021
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Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Non-bloody diarrhea, fevers and weight loss in a 70 year old man.  
    Tofani C and Kastenberg D., Adv Res Gastroenterol Hepatol 3(1):555605, 2017
  • Idiopathic Myointimal hyperplasia of mesenteric veins (IMHMV): A rare cause of refractory colitis.  
    Korenblit J, Matro R, Goldstein S, DiMarino AJ, Burkhart A, Frankel R, Klinge M, Greenbaum L, Kastenberg D., Am Surg 80(6):E152-154, 2014
  • Adenoma detection on repeat colonoscopy after previous inadequate preparation.  
    Smith CL, Roy A, Kalra AP, Daskalakis C, Kastenberg D., J Clin Gastro Hepatol Res 2(12):911-916, 2013
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Abstracts/Posters

  • Successful completion of screening and surveillance colonoscopy within a direct access colonoscopy program is non-inferior to office scheduled colonoscopy.
    White M, Israilevich R, McCarthy M, Mico V, Chipkin B, Lam S, Abrams E, Moore K, Kastenberg DM., (Poster of Distinction at DDW, 2021), 2021
  • Hiatal hernia size and Barrett’s esophagus segment length - independent predictors of the number of radiofrequency ablations needed to achieve complete eradication of ...
    Shinn B, Tofani C, Kastenberg D, Elden A, Coben R, et al., (Presented at DDW, 2020), 2020
  • A single academic center’s experience with direct access colonoscopy.
    White M, Israilevich R, Lam S, Chipkin B, Kastenberg D., (Presented at ACG 2020), 2020
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Press Mentions

  • Bid Bacon Bye-Bye: Deemed Cancer Risk
    Bid Bacon Bye-Bye: Deemed Cancer RiskNovember 1st, 2015
  • Philadelphia's Thomas Jefferson University Hospital Opens Barrett's Esophagus Treatment Center
    Philadelphia's Thomas Jefferson University Hospital Opens Barrett's Esophagus Treatment CenterFebruary 13th, 2016

Grant Support

  • “Clinical validation of an optimized multi-target stool DNA (mt-sDNA 2.0) test for colorectal cancer screening,”Exact Sciences2021
  • “PREEMPT CRC: Prevention of colorectal cancer through multiomics blood testing,”Freenome2021
  • “A Phase 3 Prospective, Randomized, double-blinded, placebo-controlled clinical study to evaluate the efficacy and safety of Rebiotix RBX2660 (microbiota suspension) for the prevention of recurrent,"Rebiotix2019
  • “Prospective Collection of PillCam SB3 videos and raw data files with abnormal findings for Future Developments,”Medtronic2019
  • “A Phase 4 Open-Label Study to Evaluate Vedolizumab IV Dose Optimization on Treatment Outcomes In Nonresponders With Moderately to Severely Active Ulcerative Colitis,”Takeda2018
  • “A multicenter, prospective, randomized study comparing the diagnostic yield of colon capsule endoscopy versus computed tomography colonography in a screening population,”Medtronic2016
  • “A multicenter, consecutive, randomized study to optimize the bowel preparation regimen for the PillCam COLON 2 capsule endoscopy procedure,”Medtronic2015
  • “Validate a new practical and simplified colonoscopy bowel preparation scale,”Ferring Pharmaceuticals2014
  • “Randomized, double-blind, placebo-controlled trial of MUC1 vaccine in patients with newly diagnosed advanced adenomas,”NCI/Cancer Prevention Network2013
  • “The impact of a purgative formulary change on the quality and cost of colonoscopy in inpatients,”Salix Pharmaceuticals2011
  • “The incidence of hyponatremia with two commonly prescribed purgatives for colonoscopy - polyethylene glycol 3350 with a sports drink (PEG-SD) compared to polyethylene glycol 3350 with electrolyte,"Salix Pharmaceuticals2010
  • "Comparison of MiroCam® Capsule Endoscope with PillCam™ SB2 Capsule Endoscope in Small Bowel Disease,"IntroMedic2010
  • "Evaluate administration of colon purgative entirely in the AM for PM colonoscopy and comparing this to standard split dose schedule,"Salix Pharmaceuticals2008
  • "To study whether providing an endoscopy report following a procedure improves patient satisfaction,"Olympus Corporation2007
  • "Colon cleansing efficacy and safety of a new microcystalline cellulose-free formulation of sodium phosphate free (INK-102) compared to Viscicol Tablets (INK-101): An investigator-blinded, randomized"InKine Pharmaceutical2004
  • "To study whether proton pump inhibitor use improves the tolerance of a colonoscopy purgative,"AstraZeneca2003
  • "To evaluate the safety of sodium phosphate tablets in patients receiving propofol-based sedation for colonoscopy,"InKine Pharmaceutical2001

Committees

  • Associate Member, Molecular Oncologu Regulation & Approaches (MORA) Program of Excellence, Sidney Kimmel Cancer Center 2022 - Present
  • Co-Chair, Joint Accreditation Advisory Committee 2019 - Present
  • Director, Clinical Research, Gastroenterology 2015 - Present
  • Member, Jefferson Joint Accreditation Professional Advisory Committe 2015 - Present
  • Co-Director, Jefferson Celiac Disease Center 2011 - Present
  • Member, Jefferson Inflammatory Bowel Disease Center 2010 - Present
  • Member, Clinical Practice Committee, GI Division 2009 - Present
  • Member, Sidney Kimmel Medical College (SKMC) Admissions Committee 2005 - Present
  • Member, Internal Medicine Residency Program Director Search Committee, Thomas Jefferson University 2022 - 2022
  • Member, Jefferson Clinical Research Council 2021 - 2023
  • GI Bleeding Disease Focused Panel, Society of Abdominal Radiology 2021 - 2021
  • Scientific Advisory, Motus GI 2019 - 2020
  • Chair, Abstract Selection Subcommittee for Colon Cancer Prevention, American College of Gastroenterology 2019 - 2019
  • Scientific Advisor, Medtronic 2018 - 2022
  • Member, Colon Abstract Review Committee, American College of Gastroenterology 2017 - 2020
  • Scientific Advisory Board, Salix Pharmacy 2017 - 2017
  • Scientific Advisory Board, Ferring Pharmaceutical 2016 - 2019
  • Member, Self-Assessment Test Committee, American College of Gastroenterology 2015 - 2020
  • Member, Education Affairs Committee, American College of Gastroenterology 2014 - 2020
  • Chair, Jefferson Medical College CME Committee 2012 - 2019
  • Member, GI and Transplant Service Line Committee 2011 - 2020
  • Member, P&T Subcommittee, Gastroenterology and Transplant 2011 - 2013
  • Member, Committee on Continuing Medical Education 2011 - 2012
  • Member, Faculty Advisory Committee on Professionalism 2009 - 2010
  • Scientific Advisory Board, Norgine Pharmaceutical 2008 - 2008
  • Member, Professional Faculty Conduct Committee 2007 - 2009
  • Scientific Advisory Board, Elan Pharmaceutical 2007 - 2007
  • Scientific Advisory Board, Salix Pharmaceutical 2005 - 2015
  • Member, Clinical Competency Committee, GI Division 1998 - 2019
  • Member, Jefferson Internal Medicine Residency Admissions Committee 1994 - 2005

Professional Memberships