ClaudineIsaacsMDFRCPC
Oncology • Washington, DCBreast Cancer, Cancer Genetics/Cancer Risk Assessment
Professor, Medicine, MedStar Georgetown University Hospital, Georgetown University Medical Center
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Office
3800 Reservoir Rd NW
Washington, DC 20007Phone+1 202-444-2223
Education & Training
Georgetown University HospitalFellowship, Medical Oncology, 1993
MedStar Health/Georgetown-Washington Hospital CenterFellowship, Hematology and Medical Oncology, 1993
McGill University Faculty of MedicineClass of 1987
Certifications & Licensure
DC State Medical License 1993 - 2024
MD State Medical License 2011 - 2014- American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- America's Top Doctors Castle Connolly, 2006-2022
- Top Doctors: Washington DC Washingtonian Magazine, 2012, 2015-2022
- America's Top Doctors for Cancer Castle Connolly, 2005-2022
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Clinical Trials
- I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer Start of enrollment: 2010 Mar 01
- Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer Start of enrollment: 2011 Jan 06
- Dovitinib Plus an Aromatase Inhibitor for Metastatic Breast Cancer Start of enrollment: 2012 Apr 01
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Publications & Presentations
PubMed
- 19 citationsLong-term follow-up assessment of cardiac safety in SAFE-HEaRt, a clinical trial evaluating the use of HER2-targeted therapies in patients with breast cancer and compr...Katia E. Khoury, Filipa Lynce, Ana Barac, Xue Geng, Chau T. Dang
Breast Cancer Research and Treatment. 2021-01-05 - 30 citationsSAFE‐HEaRt: Rationale and Design of a Pilot Study Investigating Cardiac Safety of HER2 Targeted Therapy in Patients with HER2‐Positive Breast Cancer and Reduced Left V...Filipa Lynce, Ana Barac, Ming Tan, Federico M. Asch, Karen L. Smith
The Oncologist. 2017-05-01 - 51 citationsSorafenib or Placebo with Either Gemcitabine or Capecitabine in Patients with HER-2–Negative Advanced Breast Cancer That Progressed during or after BevacizumabLee S. Schwartzberg, Kurt W. Tauer, Robert Hermann, Grace Makari-Judson, Claudine Isaacs
Clinical Cancer Research. 2013-05-15
Journal Articles
- Association of Circulating Tumor DNA and Circulating Tumor Cells After Neoadjuvant Chemotherapy with Disease Recurrence in Patients with Triple-Negative Breast CancerRita Nanda, Carla Falkson, Filipa C Lynce, Claudine Isaacs, Marcelo Blaya, Elisavet Paplomata, Radhika Walling, Reshma Mahtani, Tarah J Ballinger, Kathy D Miller, Brya..., JAMA Oncology
Other
- Genetic testing for hereditary breast and ovarian cancer syndromeIsaacs C, Peshkin BN, Fletcher SW
http://www.uptodate.com/contents/genetic-testing-for-hereditary-breast-and-ovarian-cancer-syndrome
UpToDate, Wolters Kluwer Health - 2012-08-13 - Management of hereditary breast and ovarian cancer syndrome and patients with BRCA mutationsIsaacs C, Peshkin BN, Fletcher SW
http://www.uptodate.com/contents/management-of-hereditary-breast-and-ovarian-cancer-syndrome-and-pat
UpToDate, Wolters Kluwer Health - 2013-04-10 - Characteristics of hereditary breast and ovarian cancer syndromesIsaacs C, Peshkin BN
http://www.uptodate.com/contents/characteristics-of-hereditary-breast-and-ovarian-cancer-syndromes
UpToDate, Wolters Kluwer Health - 2012-12-11 - Join now to see all
Authored Content
- Association of Circulating Tumor DNA and Circulating Tumor Cells After Neoadjuvant Chemotherapy with Disease Recurrence in Patients with Triple-Negative Breast CancerJuly 2020
Press Mentions
Anti-PD-1/Anti-LAG-3 Combination Highly Effective in HER2-Negative Breast CancerDecember 20th, 2022- High Rates of pCR with Novel Neoadjuvant Combination for Breast CancerDecember 11th, 2022
- Breast Cancer Myths vs. Facts | VerifyOctober 28th, 2022
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