CangNguyenDOFacial Plastic Surgeon

PubMed

• 31 citations
  Biliary obstruction results in PD-1-dependent liver T cell dysfunction and acute inflammation mediated by Th17 cells and neutrophils
  Lauren A. Licata, Cang T. Nguyen, Rachel A. Burga, Vincent Falanga, N. Joseph Espat
  Journal of Leukocyte Biology. 2013-10-01
• 166 citations
  Liver myeloid-derived suppressor cells expand in response to liver metastases in mice and inhibit the anti-tumor efficacy of anti-CEA CAR-T
  Rachel A. Burga, Mitchell Thorn, Gary Point, Prajna Guha, Cang T. Nguyen
  Cancer Immunology, Immunotherapy. 2015-04-08
• 21 citations
  Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor
  Steven C. Katz, Rachel A. Burga, Seema Naheed, Lauren A. Licata, Mitchell Thorn
  Journal of Translational Medicine. 2013-02-21

Journal Articles

• Hemorrhagic thyroid nodule resulting in expanding neck hematoma following blunt cervical trauma  
  Nguyen CT, Bunevich J, Ear, Nose & Throat Journal, 1/1/2018
• Liver myeloid-derived suppressor cells expand in response to liver metastases in mice and inhibit the anti-tumor efficacy of anti-CEA CAR-T  
  Burga RA, Thorn M, Point GR, Guha P, Nguyen CT, Licata LA, DeMateo RP, Ayala A, Espat NJ, Junghans RP, Katz SC., Cancer Immunology, Immunotherapy, 1/1/2015
• Liver metastases induce reversible hepatic B cell dysfunction mediated by Gr-1+CD11b+ myeloid cells  
  Thorn M, Point GR, Burga RA, Nguyen CT, Espat NJ, Katz SC., Journal of Leukocyte Biology, 1/1/2014
• Biliary obstruction results in PD-1-dependent liver T cell dysfunction and acute inflammation mediated by Th17 cells and neutrophils  
  Licata LA, Nguyen CT, Burga RA, Falanga V, Espat NJ, Ayala A, Thorn M, Junghans RP, Katz SC, Journal of Leukocyte Biology, 1/1/2013
• Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor  
  Katz SC, Burga RA, Naheed S, Licata LA, Thorn M, Osgood D, Nguyen CT, Espat NJ, Fletcher JA, Junghans RP., Journal of Translation Medicine., 1/1/2013
• Obstructive jaundice expands intrahepatic regulatory T cells which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis  
  Katz SC, Ryan K, Ahmed N, Plitas G, Chaudhry UI, Kingham TP, Naheed S, Nguyen C, Somasundar P, Espat NJ, Junghans RP, DeMatteo RP, Journal of Immunology, 1/1/2011
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Abstracts/Posters

• Liver metastases suppress intrahepatic B cells immunostimulatory function.
  Thorn M, Burga RA, Nguyen CT, Espat NJ, Katz SC., Society for Surgical Oncology, 1/1/2014
• Liver myeloid-derived suppressor cells expand in response to tumor-associated GM-CSF secretion and suppress anti-CEA genetically modified T cells.
  Burga RA, Thorn M, Nguyen CT, Licata LA, Espat NJ, Junghans RP, Katz SC, Association for Academic Surgery, 1/1/2014
• Programmed death-1 promotes the expansion of pro-inflammatory Th17 cells and neutrophils in a murine model of obstructive jaundice
  Licata LA, Nguyen CT, Burga RA, Thorn M, Falanga V, Espat NJ, Ayala A, Junghans RP, Katz SC, New England Surgical Society, 1/1/2013
• Liver Myeloid-Derived Suppressor Cells Expand in Association with Tumor-Derived GM-CSF and Suppress Anti-CEA Genetically Modified T Cells in a NO-Dependent Manner.
  Burga RA, Thorn M, Nguyen CT, Licata LA, Espat NJ, Junghans RP, Katz SC, American College of Surgeons, 1/1/2013
• Targeting myeloid-derived suppressor cells and the PD-1/PD-L1 axis to enhance immunotherapy with anti-CEA designer T cells for the treatment of colorectal liver metast...
  Burga RA, Thorn M, Nguyen CT, Licata LA, Espat NJ, Junghans RP, Katz SC, American Society of Clinical Oncology, 1/1/2013
• Effects of colorectal cancer liver metastases on intrahepatic B cells.
  Thorn M, Burga RA, Nguyen CT, Licata LA, Espat NJ, Katz SC., American Association of Immunologists, 1/1/2013
• Loss of Programmed Death-1 signaling uncouples the anti-inflammatory and immunosuppressive effects of liver regulatory T cells in a model of obstructive jaundice.
  Licata LA, Nguyen CT, Burga RA, Naheed S, Wang X, Wang L, Ayala A, Junghans RP, Espat NJ, Katz SC., American College of Surgeons, 1/1/2012
• Liver Th17 cell mediated inflammation is regulated in a programmed death-1 dependent manner in a model of obstructive jaundice.
  Licata LA, Nguyen CT, Burga RA, Falanga V, Ayala A, Junghans RP, Espat NJ, Katz SC., Association for Academic Surgery and Society of University Surgeons: 8th Annual Academic Surgical Congress, 1/1/2012
• Sorafenib abrogates the expansion of CD8+ Treg following partial hepatectomy.
  Kurniali PC, Nguyen CT, Licata L, Falanga V, Espat NJ, Katz SC, American Hepato-Pancreato-Biliary Association, 1/1/2012
• IL-10 and PD-1 mediate T cell suppression in jaundiced animals with opposing effects on inflammatory cytokine production
  Licata L, Nguyen CT, Naheed S, Liu Y, Wang X, Wang L, Espat NJ, Katz SC., American Hepato-Pancreato-Biliary Association, 1/1/2012
• Anti-CEA designer T-cells are suppressed by liver myeloid suppressor cells and regional infusion enhances efficacy for the treatment of intrahepatic metastases.
  Naheed S, Ahmed N, Nguyen CT, Bais A, Ma Q, Licata L, Espat NJ, Junghans RP, Katz SC, Society of Surgical Oncology Annual Cancer Symposium, 1/1/2012
• Pre-clinical testing of anti-KIT designer T-cells for the treatment of gastrointestinal stromal tumor.
  Naheed S, Bias A, Ahmed N, Nguyen CT, Licata L, Espat NJ, Junghans RP, Katz SC, Annals of Surgical Oncology, 1/1/2012
• Reversing the immunosuppressive effects of liver regulatory T cells while maintaining their anti-inflammatory properties by blocking programmed death-1.
  Licata L, Nguyen CT, Naheed S, Liu Y, Wang X, Wang L, Ayala A, Junghans RP, Espat NJ, Katz SC., New England Immunology Conference, 1/1/2011
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