ArielLopez ChavezMDMS(He/Him)

PubMed

• 1913 citations
  First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer
  Leora Horn, Aaron S. Mansfield, Aleksandra Szczesna, Libor Havel, Maciej Krzakowski
  The New England Journal of Medicine. 2018-09-25
• 2413 citations
  Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
  Mark A. Socinski, Robert M. Jotte, Federico Cappuzzo, Francisco Orlandi, Daniil Stroyakovskiy
  The New England Journal of Medicine. 2018-06-04
• 1127 citations
  Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063):...
  Naiyer A. Rizvi, Julien Mazieres, David Planchard, Thomas E. Stinchcombe, Grace K. Dy
  The Lancet. Oncology. 2015-03-01

Journal Articles

• Molecular Profiling and Targeted Therapy for Advanced Thoracic Malignancies: A Biomarker-Derived, Multiarm, Multihistology Phase II Basket Trial  
  Lopez-Chavez A, Thomas A, Rajan A, Raffeld M, Morrow B, Kelly R, Carter CA, Guha U, Killian K, Lau CC, Abdullaev Z, Xi L, Pack S, Meltzer PS, Corless CL, Sandler A, Be..., J Clin Oncol, 1/9/2015
• Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063):...  
  Rizvi NA, Mazieres J, Planchard D, Stinchcombe TE, Dy GK, Antonia SJ, Horn L, Lena H, Minenza E, Mennecier B, Otterson GA, Campos LT, Gandara DR, Levy BP, Nair SG, Zal..., Lancet Oncol, 1/1/2015
• Association of patient characteristics with chemotherapy receipt among depressed and non-depressed patients with non-small cell lung cancer  
  Sullivan DR, Ganzini L, Lopez-Chavez A, Slatore CG, Psycho-Oncology, 1/28/2014
• A Phase I/II Trial of Belinostat in Combination with Cisplatin, Doxorubicin and Cyclophosphamide in Thymic Epithelial Tumors: A Clinical and Translational Study  
  Thomas A, Rajan A, Szabo E, Tomita Y, Carter CA, Scepura B, Lopez-Chavez A, Lee MJ, Redon CE, Frosch A, Peer CJ, Chen Y, Piekarz RL, Steinberg SM, Trepel JB, Figg W, S..., Clin Cancer Res, 1/4/2014
• Elderly Former Smoker with HRAS Mutant Non-Small-Cell Lung Cancer  
  Cathcart-Rake E, Corless C, Sauer D, Lopez-Chavez A, J Thorac Oncol, 1/1/2014
• Young male with fanconi anemia and EGFR-mutant non-small-cell lung cancer  
  Cathcart-Rake E, Lopez-Chavez A, J Thorac Oncol, 1/1/2014
• From Platinum Compounds to Targeted Therapies in Advanced Thoracic Malignancies  
  Jakopovic, M., Thomas, A., Lopez-Chavez, A., Anticancer Res, 1/1/2014
• Treatment Receipt and Outcomes among Lung Cancer Patients with Depression  
  Sullivan, D.R., Ganzini, L., Duckart, J.P., Lopez-Chavez, A., Deffebach, M.E., Thielke, S.M., Slatore, C.G., Clinical Oncology, 1/1/2014
• Cixutumumab for patients with recurrent or refractory advanced thymic epithelial tumours: a multicentre, open-label, phase 2 trial  
  Rajan, A., Carter, C.A., Berman, A., Cao, L., Kelly, R.J., Thomas, A., Khozin, S., Lopez-Chavez, A., Bergagnini, I., Scepura, B., Szabo, E., Lee, M.-J., Trepel, J.B., ..., The Lancet Oncology, 1/1/2014
• A phase I/II study of sepantronium bromide (YM155, survivin suppressor) with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer  
  Kelly RJ, Thomas A, Rajan A, Chun G, Lopez-Chavez A, Szabo E, Spencer S, Carter CA, Guha U, Khozin S, Poondru S, Van Sant C, Keating A, Steinberg SM, Figg W, Giaccone G, Ann Oncol, 1/14/2013
• From targets to targeted therapies and molecular profiling in non-small cell lung carcinoma  
  Thomas A, Rajan A, Lopez-Chavez A, Wang Y, Giaccone G, Ann Oncol, 1/1/2013
• Neuroendocrine ACTH-Producing Tumor of the Thymus-Experience with 12 Patients over 25 Years  
  Neary NM, Lopez-Chavez A, Abel BS, Boyce AM, Schaub N, Kwong K, Stratakis CA, Moran CA, Giaccone G, Nieman LK, J Clin Endocrinol Metab, 1/16/2012
• Systemic issues in small cell lung cancer  
  Lopez-Chavez A, Sandler A, Curr Probl Cancer, 1/1/2012
• HGF Airway Over-expression Leads to Enhanced Pulmonary Vascularization without Induction of VEGF  
  Henry C, Lopez-Chavez A, Stabile LP, Siegfried JM, Current Angiogenesis, 1/1/2012
• Bevacizumab maintenance in patients with advanced non-small-cell lung cancer, clinical patterns, and outcomes in the Eastern Cooperative Oncology Group 4599 Study: res...  
  Lopez-Chavez A, Young T, Fages S, Leon L, Schiller JH, Dowlati A, Brahmer JR, Johnson DH, Sandler A, J Thorac Oncol, 1/1/2012
• Phase II study of belinostat in patients with recurrent or refractory advanced thymic epithelial tumors  
  Giaccone G, Rajan A, Berman A, Kelly RJ, Szabo E, Lopez-Chavez A, Trepel J, Lee M, Cao L, Espinoza-Delgado I, Spittler J, Loehrer P, J Clin Oncol, 1/20/2011
• Characterization of epidermal growth factor receptor mutations in non-small-cell lung cancer patients of African-American ancestry  
  Harada T, Lopez-Chavez A, Xi L, Raffeld M, Wang Y, Giaccone G, Oncogene, 1/14/2011
• Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin  
  Kelly RJ, Lopez-Chavez A, Citrin D, Janik JE, Morris JC, Mol Cancer, 1/6/2011
• Evaluation of KRAS Mutations, Angiogenic Biomarkers, and DCE-MRI in Patients with Advanced Non-Small-Cell Lung Cancer Receiving Sorafenib  
  Kelly, R., Jeremy Force, Arun Rajan, Lopez-Chavez, A., Martin Gutierrez, Corrine Keen, Liang Cao, Baris Turkbey, Mark Raffeld, Liqiang Xi, Seth M. Steinberg, John J. W..., Clin Cancer Res, 1/1/2011
• Criteria of Evidence to Move Potential Chemopreventive Agents into Late Phase Clinical Trials  
  Kelly RJ, Lopez-Chavez A, Szabo E, Curr Drug Targets, 1/15/2010
• The role and importance of anti-angiogenesis in oncology  
  Lopez-Chavez, A., Giaccone, G., Angiog Journ, 1/1/2010
• Targeted therapies: Importance of patient selection for EGFR TKIs in lung cancer  
  Lopez-Chavez, A., Giaccone, G., Nature Reviews Clinical Oncology, 1/1/2010
• The role of KRAS mutations in resistance to EGFR inhibition in the treatment of cancer  
  Lopez-Chavez, A., Carter, C.A., Giaccone, G., Curr Opin Investig Drugs, 1/1/2009
• Cloning and functional expression of the bovine GABAC rho2 subunit Molecular evidence of a widespread distribution in the CNS  
  Lopez-Chavez, A., Miledi, R., Martinez-Torres, A., Neurosci Res, 1/1/2005
• Medications That Cause Cough  
  Gomez-Lopez, Enrique, Lopez-Chavez, A., Gaceta Medica UAQ, 1/1/2002
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Books/Book Chapters

• Emerging Therapies in Lung Cancer 
  Chapter: VEGF Inhibitors. 
  Lopez-Chavez, A. Sandler, A.2012
• Lung Cancer Choices 
  Chapter: Treatment of Small Cell Lung Cancer. 
  Lopez-Chavez, A.Editors: Caring Ambassadors Program, Inc..Edition 1st,2012
• Atlas of Dermatology 
  Lopez-Chavez, Ariel, Rodolfo Perez-QuinteroEdition 2nd,2005
• Atlas of Rheumatology 
  Barreira Mercado, Eduardo, Ventura Hernandez, Viviana, Lopez-Chavez, ArielEditors: MediUAQ, Universidad Autonoma de Queretaro.2005
• Atlas of Plain Radiology of the Thorax 
  Perez-Aguinaga, Maria, Salmon Velez, Jesús, Lopez-Chavez, ArielEditors: MediUAQ, Universidad Autonoma de Queretaro.2005
• Atlas of Dermatology 
  Lopez-Chavez, Ariel, Rodolfo Perez-QuinteroEdition 1st,2002
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Abstracts/Posters

• A phase 2 study of defactinib (VS-6063), a cancer stem cell inhibitor that acts through inhibition of focal adhesion kinase (FAK), in patients with KRAS-mutant non-sma...
  David E. Gerber, Suresh S. Ramalingam, Daniel Morgensztern, Ronan Joseph Kelly, Timothy Francis Burns, Ariel Lopez-Chavez, David R. Spigel, Ahmad Mouhamad Wehbe, Rache..., Journal of Clinical Oncology, 2014 ASCO Annual Meeting Abstracts, 1/20/2014
• David E. Gerber, Toby Christopher Campbell, Paul Swanson, Ariel Lopez-Chavez, Lucas Wong, Afshin Dowlati, Amy Qin, Jan G. C. E., Journal of Clinical Oncology, 2014 ASCO Annual Meeting Abstracts., 1/1/2014
• A randomized phase 2 trial of MM-121, a fully human monoclonal antibody targeting ErbB3, in combination with erlotinib in EGFR wild-type NSCLC patients.
  Lecia V. Sequist, Ariel Lopez-Chavez, Robert Charles Doebele, Jhanelle Elaine Gray, Wael A. Harb, Manuel R. Modiano, David Michael Jackman, Maria Quintos Baggstrom, Ak..., Journal of Clinical Oncology, 2014 ASCO Annual Meeting Abstracts, 1/1/2014
• Tumor genotype and clinical outcomes for 229 patients with non-small cell lung cancer.
  Regan M. Duffy, Grant Roesler, Andrea Warrick, Carol Beadling, Kathryn Schuff, Christopher L. Corless, Alan Sandler, Ariel Lopez-Chavez, J Clin Oncol, 1/1/2013
• CUSTOM (Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies trial): A radical redesign of...
  Ariel Lopez-Chavez, Anish Thomas, Arun Rajan, Seth M. Steinberg, David M. Dilts, Austin Doyle, Giuseppe Giaccone, J Clin Oncol, 1/1/2013
• Custom (Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies) trial.
  Giuseppe Giaccone, Ariel Lopez-Chavez, Anish Thomas, Arun Rajan, Mark Raffeld, Regan M. Duffy, Betsy Morrow, Yisong Wang, Corey Allan Carter, Udayan Guha, Keith Killia..., J Clin Oncol, 1/1/2013
• Pilot trial of molecular profiling and targeted therapies in advanced thoracic malignancies: Non-small cell lung cancer, small cell lung cancer and thymic malignancies...
  Ariel Lopez-Chavez, Arun Rajan, Anish Thomas, Mark Raffeld, Liqiang Xi, Paul S. Meltzer, Regan M. Duffy, Svetlana Pack, Alan Sandler, Christopher L. Corless, Keith Kil..., Journal of Clinical Oncology, 2012 ASCO Annual Meeting Abstracts, 1/20/2012
• Early Prediction of Breast Cancer Therapeutic Response and Evaluation of Residual Disease Using Quantitative DCE-MRI.
  Alina Tudorica, Karen Y Oh, Stephen Y-C Chui, Nicole Roy, Megan L Troxell, Yiyi Chen, Arpana Naik, Ariel Lopez-Chavez, Megan L Holtorf, Aneela Afzal, Mohan Jayatilake,..., ISMRM, 1/1/2012
• A phase I study of paclitaxel, carboplatin, and YM155 (survivin suppressor) in subjects with solid tumors.
  R. J. Kelly, A. Rajan, G. Chun, A. Lopez-Chavez and G. Giaccone, Journal of Clinical Oncology, 2011 ASCO Annual Meeting Abstracts, 1/20/2011
• Management of thymic epithelial tumors (TETs) at the National Cancer Institute (NCI).
  A. Rajan, R. J. Kelly, A. Lopez-Chavez, C. A. Carter, E. Szabo, B. Scepura, M. J. (. Manu, A. W. Berman and G. Giaccone, Journal of Clinical Oncology, 2011 ASCO Annual Meeting Abstracts, 1/20/2011
• Phase II study of the insulin-like growth factor-1 receptor (IGF-1R) antibody cixutumumab (C) in patients (Pts) with thymoma (T) and thymic carcinoma (TC).
  Rajan, A., Berman, A.W., Kelly, R.J., Lopez-Chavez, A., Dechowdhury, R., Chen, H., Giaccone, G., Journal of Clinical Oncology, 2010 ASCO Annual Meeting Abstracts, 1/20/2010
• Neuroendocrine ACTH producing carcinoma of the thymus (NDASH) experience with 10 patients.
  Neary, N., Lopez-Chavez, A., Giaccone, G., Nieman, L., ENDO 2010: The 92nd Annual Meeting & Expo, 1/1/2010
• Belinostat treatment in recurrent thymoma or thymic carcinoma.
  Giaccone, G., Rajan, A., Kelly, R., Carter, C.A., Lopez-Chavez, A., Berman, A., Spittler, J., Espinoza-Delgado, M., Trepel, J., Loehrer, P., 1st International Conference on Thymic Malignancies, Bethesda, MD, 1/1/2009
• Evidence of VEGF downregulation in carcinogen-induced lung tumors from transgenic mice overexpressing human HGF in the small airways.
  Lopez-Chavez, A., Brizzi, K., Stabile, L.P., Siegfried, J.M., AACR Annual Meeting, Los Angeles, CA, 1/1/2007
• MediUAQ, bridging the digital divide of internet based medical education in Latin America. Unexpected outcomes from a pilot website revealing a growing need.
  Lopez-Chavez A, Perez-Quintero R, Mednet 2006: 11th World Congress on the Internet in Medicine and the Society for Internet in Medicine, Toronto, Canada, 1/1/2006
• MediUAQ, bridging the gap of internet based medical education in Rheumatology and Dermatology for the Latin American community.
  Lopez-Chavez A, Barreira ME, Perez-Quintero R, Ventura HV, Journal of Clinical Rheumatology, 1/1/2006
• MediUAQ, bridging the gap of internet based medical education for the Hispanic community. Unexpected outcomes from a pilot website revealing a growing need.
  Lopez-Chavez A, Dana-Farber/ Harvard Cancer Center Junior Investigators' health Disparities Research Poster Session, Harvard Medical School, Boston, MA, 1/1/2006
• GABA-responses of receptors formed by GABA rho-1 and gamma-2 (K289M).
  Trejo-Medinilla, F.M., Lopez-Chavez, A., Garcia-Alcocer, G., Miledi, R., Martinez-Torres, A., 30th FEBS Congress - 9th IUBMB Conference, 1/1/2005
• Molecular Heterogeneity of GABAc Receptors in the Caudate Nucleus.
  Opperman, E., Lopez-Chavez, A., Miledi, R., Martinez-Torres, A., American Academy for the Advancement of Science Annual Meeting, Washington, DC, 1/1/2005
• Mapping of GABAc Receptor rho Subunits in the Human CNS.
  Kasravi, S., Lopez-Chavez, A., Miledi, R., Martinez-Torres, A., American Academy for the Advancement of Science Annual Meeting, Washington, DC, 1/1/2005
• Molecular Heterogeneity of GABAc Receptors in the Caudate Nucleus.
  Opperman, E., Lopez-Chavez, A., Miledi, R., Martinez-Torres, A., 23rd Annual Career Opportunities in Research Colloquium, National Institute of Mental Health, San Juan, Puerto Rico, 1/1/2004
• Mapping of GABAc Receptor rho Subunits in the Human CNS.
  Kasravi, S., Lopez-Chavez, A., Miledi, R., Martinez-Torres, A., Annual Biomedical Research Conference for Minority Students, Dallas, TX, 1/1/2004
• Distribution, Molecular Cloning and Functional Characterization of GABAc Receptor rho Subunits from the Bovine CNS.
  Lopez-Chavez, A., Miledi, R., Martinez-Torres, A., 4th Forum of the Federation of European Neuroscience Societies, Lisbon, Portugal, 1/1/2004
• Distribution of the GABAc rho3 Subunit in the Bovine Central Nervous System.
  Hernandez, Melissa, Maria Eugenia Perez-Aguinaga, Lopez-Chavez, A, Ricardo Miledi, Ataulfo Martinez-Torres, Luis Mota-Bravo, Annual Biomedical Research Conference for Minority Students, San Diego, CA, 1/1/2003
• Modifications in the Concentration of Glucose and Lactic Acid in Rats Subjected to Hypothermia and Treated with Thiamine Pyrophosphate.
  Lopez-Chavez, A, Ulises Godoy-Garcia, Maria Guadalupe Puga- Sanchez, Susana Alcazar-Leyva XIII, National Forum of Medical Sciences and Physical Culture Students, Santiago de Cuba, Cuba, 1/1/1998
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Lectures

• Molecular Profiling and Targeted Therapies in Advanced Thoracic Malignancies, The CUSTOM trial experience. 
  Miami, FL - 1/1/2013
• Tarceva and Avastin in Lung Cancer. 
  Boise, ID - 1/17/2012
• An Evolving Treatment Strategy for Advanced Nonsquamous NSCLC with ALIMTA. 
  Hood River, OR - 1/8/2012
• Cancer Prevention, Treatment and Survivorship in Latinos. 
  Portland, OR - 1/1/2012
• An Evolving Treatment Stragegy for Advanced Nonsquamous NSCLC with ALIMTA. 
  Salem, OR - 1/1/2012
• Avastin in Lung Cancer. 
  Ashland, OR - 1/1/2012
• Updates in Non-Small Cell Lung Cancer 2012. 
  Oregon Health and Science University, Portland, OR - 1/1/2012
• From platinum drugs to targed therapies. 
  Verona, Italy - 1/1/2012
• Lung Cancer Updates 
  San Francisco, CA - 1/1/2012
• Updates in Non-Small Cell Lung Cancer 2011. 
  Oregon Health and Science University, Portland, OR - 1/1/2011
• Advances in the treatment of small cell lung cancer. 
  Salishan, OR - 1/1/2011
• Advances in adjuvant therapy for non-small cell lung cancer. 
  Salishan, OR - 1/1/2011
• Molecular Profiling and Targeted Therapies in Advanced Thoracic Malignancies. 
  Houston, TX - 1/1/2010
• Molecular Profiling and Target Therapies in Advanced Thoracic Malignancies. 
  Portland, OR - 1/1/2010
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Other

• Cancer de Mama: Que es la neuropatia? 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Efectos adversos communes de la quimioterapia. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Como se de la quimioterapia? 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: La Quimioterapia. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: HER2. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Importancia de la Hormonas. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Estadios del Cancer de Mama. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Tipos de Cancer de Mama. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Dos cosas importantes que toda mujer con cancer de mama - tiene que saber. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Terapias Hormonales. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Quimioterapia. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Radiacion. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Cirugia. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer de Mama: Que es la neutropenia? 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/26/2013
• Cancer De Mama: Como se trata? 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/24/2013
• Cancer de Mama: Quien es el Cirujano Oncologo? 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/23/2013
• Cancer de Mama: Quien es el Oncologo Radioterapista? 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/22/2013
• Cancer de Mama: Quien es el Oncologo Medico? 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/22/2013
• Derrame Pleural: Lo basico. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/22/2013
• Meningitis: Lo basico. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/22/2013
• Seguro Medico y Reforma de Salud: costo del seguro medico. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/22/2013
• Pericarditis: Lo basico. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/21/2013
• Rinitis: Lo basico. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/21/2013
• Neumonitis: Lo basico. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/21/2013
• Cancer de Mama: Medicos Especialistas en el Tratamiento del Cancer de Mama. 
  Lopez-Chavez, A., SisaludTV
  www.youtube.com
  1/21/2013
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