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Office
188 Valley Street
Suite 424
Providence, RI 02909Phone+1 401-272-2123Fax+1 401-272-7562
Summary
- Dr. Annie De Groot is a board-certified Internal Medicine physician who has primarily focused on biotechnology over the past 26 years. As founder and CEO of the EpiVax biotech company, based in Providence, Rhode Island, she has contributed to the development of new computational tools and methodologies for designing, developing, and approval of products in the Autoimmunity, Allergy, Immunology and Infectious Disease fields. She completed her education and early training at the University of Chicago and Tufts New England Medical Center. She was fellow in the Geographic Medicine (Infectious Diseases) program at NEMC, and she also completed a fellowship in vaccinology under Jay Berzofsky at the NIH (NIAID and NCI). Currently, she maintains a C-suite position at EpiVax, the company she established in Providence, Rhode Island in 1998. Her previous academic positions have included Senior Research Scientist at the University of Georgia and Director of the Institute for Immunology and Informatics at the University of Rhode Island. She was also faculty at the Brown University School of Medicine (now Warren Alpert Medical School). She is founder and board member of Clinica Esperanza/Hope Clinic, and GAIA Vaccine Foundation. Over the years, she has obtained research experience in immunology, vaccines, computational vaccinology, and providing free healthcare for the uninsured. She is widely published and has won awards including the AAPS Pharmaceutical Global Health Award and the Distinguished Alumni Award from University of Chicago Pritzker School of Medicine.
Education & Training
- Tufts Medical CenterFellowship, Infectious Disease, 1989 - 1992
- National Institutes of Health Clinical CenterFellowship, Allergy and Immunology, 1986 - 1989
- Tufts Medical CenterResidency, Internal Medicine, 1983 - 1986
- University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1983
- Smith CollegeB.A., 1974 - 1978
Certifications & Licensure
- MA State Medical License 1991 - 2026
- RI State Medical License 1992 - 2026
- CT State Medical License 1996 - 2006
- DC State Medical License 1986 - 1990
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- 2020 AAPS Pharmaceutical Global Health Award American Association of Pharmaceutical Scientists, 2020
- Distinguished Alumni Award University of Chicago Pritzker School of Medicine, 2019
- CEO of the Year (2016) World Vaccine Congress, 2016
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Publications & Presentations
PubMed
- 4 citationsIn silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies.Aimee E Mattei, Andres H Gutierrez, Soorya Seshadri, Jacob Tivin, Matt Ardito
Mabs. 2024-03-27 - 2 citationsNeoadjuvant personalized cancer vaccines: the final frontier?Guilhem Richard, Nicole Ruggiero, Gary D Steinberg, William D Martin, Anne S De Groot
Expert Review of Vaccines. 2024-01-10 - 7 citationsOptimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning.Emily K Makowski, Tiexin Wang, Jennifer M Zupancic, Jie Huang, Lina Wu
Nature Biomedical Engineering. 2024-01-01
Journal Articles
- In Silico Vaccine Design: Accelerating the Response to BioThreats and Emerging Infectious DiseaseLenny Moise, Sarah Beseme, and Anne S. De Groot, IQT Quarterly, 1/1/2016
- C3d adjuvant effects are mediated through the activation of C3d-specific autoreactive T cellsDe Groot AS, Ross TM, Levitz L, Messitt TJ, Tassone R, Boyle CM, Vincelli AJ, Moise L, Martin W, Knopf PM, Immunol Cell Biol, 1/1/2015
- Aspartate-beta-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinomaTomimaru Y, Mishra S, Safran H, Charpentier KP, Martin W, De Groot AS, Gregory SH, Wands JR, Vaccine, 1/1/2015
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Books/Book Chapters
Abstracts/Posters
- Development of Community-led Education Interventions for Human Papillomavirus Vaccination as a Model for Future HIV Vaccination CampaignsKaramoko Tounkara, Ibrahima Teguete, Eliza Squibb, Ben Aboubacar, Kotou Sangare, Sarah Beseme, Ousmane Koita, International Symposium for HIV and Emerging Infectious Diseases, Marseille, France, 1/25/2016
- Development of community-led education about Human papillomavirus vaccination as a model for future HIV vaccination campaignsKaramoko Tounkara, Ibrahima Teguete, Eliza Squibb, Ben Aboubacar, Kotou Sangare, Sarah Beseme, Ousmane Koita, 15th European AIDS Conference, Barcelona, Spain, 1/21/2015
- Assessment of HPV and cervical cancer knowledge, attitudes, practices and willingness to participate in an HPV vaccination program in Bamako, MaliKaramoko Tounkara, Ibrahima Teguete, Eliza Squibb, Ben Aboubacar, Youssouf Kone, Kotou Sangare, Sarah Beseme, Jennifer S. Smith, Ousmane Koita, A. S. De Groot, 30th International Papillomavirus Conference and Clinical and Public Health Workshops, Lisbon, Potrugal, 1/17/2015
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Lectures
- Personalized Medicine for Biologics: Does HLA play a role in Immunogenicity?Instituto Gulbenkian de Ciencia, Oeiras, Lisbon, Portugal - 1/23/2015
- The Two-faced T cell epitope and the role of "Sel" and "Other" in Vaccine EfficacyNetherlands National Institute for Public Health and the Environment (RIVM) and IntraVacc, Utrecht, - 1/18/2015
- Tregitope Mediated Tolerance: The Role of HLARotterdam, Netherlands - 1/17/2015
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Other
- Writings from West AfricaA. S. De Groot, GAIA Vaccine Foundation Website
http://blog.gaiavaccine.org/
1/1/2015 - Thinking Out Loud (Blog on Immunogenicity, Biotherapeutics and Vaccines)A. S. De Groot
http://www.epivax.com/blog/
1/1/2015 - Methods for Addressing Immunogenicity in Therapeutic EnzymesCousens LP, Moise L, De Groot AS, Biobetters, AAPS Advances. American Association of Pharmaceutical Scientists 2015 in the Pharmaceuti
1/1/2015 - Join now to see all
Other Languages
- Spanish, French
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