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Office
9500 Euclid Ave
Cleveland, OH 44195Phone+1 800-223-2273
Summary
- Andre Machado, M.D., Ph.D.
Chairman, Neurological Institute
Dr. Machado is the Chairman of the Neurological Institute and the Charles and Christine Carroll Family Endowed Chair in Functional Neurosurgery. Dr. Machado performs deep brain stimulation (DBS) surgery for patients with Parkinson’s disease, tremor, dystonia and obsessive-compulsive disorder as well as surgical procedures for patients with trigeminal neuralgia, intractable pain syndromes and spasticity.
Dr. Andre Machado received his medical degree from the University of Sao Paulo in 1997. He completed his residency in the same institution in 2003 and obtained his Ph.D. in 2004. He came to the Cleveland Clinic in 2004, completed his fellowship in Stereotactic and Functional Neurosurgery in 2006 and has been on the staff of the Cleveland Clinic since then.
Dr. Machado is the program director for education in Stereotactic and Functional Neurosurgery and won the “Teacher of the year award” from the Department of Neurosurgery in 2009. Dr. Machado is Full Staff in the Department of Neurosurgery with Joint Appointments in the Department of Neuroscience and in the Department of Biomedical Engineering at the Cleveland Clinic Lerner Research Institute. He is the current Chairman for the Joint Pain Section of the CNS/AANS and he is a Board Member of the American Society of Stereotactic and Functional Neurosurgery.
Dr. Machado leads several deep brain stimulation and neuromodulation clinical trials as well as laboratory research. His research in deep brain stimulation for thalamic pain syndrome was awarded the National Institutes of Health Director’s New Innovator’s Award. In addition, he conducts deep brain stimulation research for treatment refractory depression as well as obsessive compulsive disorder. His laboratory in the Lerner Research Institute is focused in developing new strategies for utilizing neuroprosthetic devices such as DBS to improve post-stroke rehabilitation. His current NIH funded research i
Education & Training
- Cleveland Clinic Center for Neurological Restoration and Department of NeurosurgeryFellowship, 2004 - 2006
- Hospital das Clinicas of the University of Sao Paulo Medical School (Faculdade de Medicina da USP)Residency, 1998 - 2003
- Univ Sao Paulo- Fac MedClass of 1997
Certifications & Licensure
- OH State Medical License 2004 - 2026
Awards, Honors, & Recognition
- Top Doctor Castle Connolly, 2014-2019
- New Innovator's Award National Institutes of Health, 2009
- Gildenberg Award American Association of Neurological Surgeons, Stereotactic and Functional Neurosurgery Section, 2006
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Clinical Trials
- Effectiveness of Deep Brain Stimulation for Treating People With Treatment Resistant Obsessive-Compulsive Disorder Start of enrollment: 2008 Mar 01
- Safety Study of Deep Brain Stimulation to Manage Thalamic Pain Syndrome Start of enrollment: 2010 May 01
- Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery Start of enrollment: 2011 Jul 01
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Publications & Presentations
PubMed
- 535 citationsBehavioural improvements with thalamic stimulation after severe traumatic brain injuryNicholas D. Schiff, Joseph T. Giacino, Kathleen Kalmar, Jonathan D. Victor, Kenneth B. Baker
Nature. 2007-08-02 - 58 citationsRethinking Stimulation of the Brain in Stroke Rehabilitation Why Higher Motor Areas Might Be Better Alternatives for Patients with Greater ImpairmentsEla B. Plow, David A. Cunningham, Nicole Varnerin, Andre G. Machado
The Neuroscientist. 2015-06-01 - 29 citationsProceedings of the Third Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and TechnologiesP. Justin Rossi, Aysegul Gunduz, Jack W. Judy, Linda Wilson, Andre G. Machado
Frontiers in Neuroscience. 2016-04-06
Journal Articles
- The Safety and Efficacy of Using the O‐Arm Intraoperative Imaging System for Deep Brain Stimulation Lead ImplantationDarlene A Lobel, Hubert H Fernandez, Andre G Machado, Sean J Nagel, Neuromodulation: Technology at the Neural Interface
Press Mentions
- What Is Cleveland Clinic’s Brain Study?June 20th, 2023
- AANS/CNS Cerebrovascular Section and American Society of Stereotactic and Functional Neurosurgery Contribute to SNS Neurosurgeon-Scientist Training ProgramJanuary 24th, 2023
- Cleveland Clinic Expands Landmark Brain Study After Receiving a $2 Million Grant from Ohio’s Department of EducationMay 6th, 2022
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Grant Support
- Dentatothalamocortical Electrical Stimulation In Post-Stroke Motor RecoveryEunice Kennedy Shriver National Institute Of Child Health &Human Development2010–2012
- Deep Brain Stimulation Of The Ventral Anterior Limb Of The Internal Capsule For MOffice Of The Director, National Institutes Of Health2009
- Cerebellar Stimulation For Motor Recovery From StrokeEunice Kennedy Shriver National Institute Of Child Health &Human Development2007–2008
Committees
- Chairman, Joint Section for Pain Executive Committee, CNS/ AANS 2015 - Present
- Board of Directors, American Society of Stereotactic and Functional Neurosurgery 2015 - Present
- Member, Guideline Task Force, Congress of Neurological Surgeons 2015 - Present
Professional Memberships
- Member
Other Languages
- Portuguese
External Links
- Cleveland Clinic Physician Profilehttp://my.clevelandclinic.org/staff_directory/staff_display?DoctorID=7277
- Cleveland Neurological Institute http://my.clevelandclinic.org/services/neurological_institute
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