Ai-XuanLHoltermanMD

PubMed

• 6 citations
  Strengthening Surgery Strengthens Health Systems: A New Paradigm and Potential Pathway for Horizontal Development in Low- and Middle-Income Countries.
  S Ariane Christie, Benedict C Nwomeh, Sanjay Krishnaswami, George P Yang, Ai-Xuan L Holterman
  World Journal of Surgery. 2019-03-01
• 64 citations
  Nonalcoholic fatty liver disease in severely obese adolescent and adult patients.
  Ai Xuan Holterman, Grace Guzman, Giamila Fantuzzi, Huaping Wang, Kristin Aigner
  Obesity. 2013-03-01
• 30 citations
  An academic career in global surgery: a position paper from the Society of University Surgeons Committee on Academic Global Surgery.
  Sanjay Krishnaswami, Caroline Q. Stephens, George P. Yang, Benedict C. Nwomeh, Mamta Swaroop
  Surgery. 2017-01-01

Journal Articles

• Autophagy modulates physiologic and adaptive response in the liver  
  Trinh Van Le, Nhung Hai Truong, Liver Research, 12/6/2023
• Study protocol of!Phase 2 open-label multicenter randomized controlled trial for!granulocyte-colony stimulating factor (GCSF) in!post-Kasai Type 3 biliary atresia  
  HPA Nguyen, J Ren, M Butler, H Li, S Qazi, K Sadiq, HT Dao, and A Holterman, Ped Surg International, 4/7/2022
• Academic pediatric surgery capacity building in Vietnam through PASS, a Pediatric Acute Surgical Support course  
  BU Nguyễn, Holterman M, Holterman A, Q Dinh, Frontiers in Surgery-Pediatric Surgery, 4/4/2022
• PASS- A course in Pediatric Acute Surgical Support to build pediatric surgical emergencies capacity in developing countries  
  T Dinh, T Khairallah, G Deshpande, C Nguyen, S Krzyzaniak, G Barton, S Bohrensen, MT Vu, and A Holterman, Journal of Pediatric Surgery, 3/13/2022
• Granulocyte-Colony Stimulating Factor GCSF mobilizes hematopoietic stem cells in Kasai patients with biliary atresia in a Phase 1 study and improves short term outcome  
  AiXuan Holterman, Hoa Pham Anh Nguyen, Evan Nadler, Giap H Vu, Parvathi Mohan, Megan Vu, Thuy Thi Trinh, Huong Thuy Thi Bui, Binh Thanh Nguyen, Anh Tran Quynh, and Hie..., J Ped Surg, 4/9/2021
• Biliary atresia liver histopathological determinants of early post-Kasai outcome  
  Anh-Hoa Pham Nguyen, Yen Hai T Pham, Giap H Vu, My Ha Nguyen, Thach Ngoc Hoang, and AiXuan Holterman, J Ped Surg, 4/2021
• Optimization of the isolation procedure and culturing conditions for hepatic stellate cell obtained from mouse  
  58. Minh Thanh Dang, Van Trinh Le, Quang Huy Do, Van Thuan Nguyen, Ai Xuan Le Holterman, Loan Tung Thi Dang, Nhan Chinh Lu Phan, Phuc Van Pham, Son Nghia Hoang, Long T..., Biosci Rep, 1/29/2021
• Recombinant human granulocyte colony-stimulating factor alleviates liver fibrosis in bile duct-ligated mice  
  Huy Quang Do, Trinh Van Le, Minh Thanh Dang, Tien-Trieu Pham-Le, Luan Van Tran, Khon Chan Huynh, Ai-Xuan Le Holterman, Nhung Hai Truong., Biomedical Research and Therapy. 6, 6 (Jun. 2019), 3222-3232., 6/2019
• The Heterogeneity of Global Pediatric Surgery: Defining Needs and Opportunities Around the World.  
  Garger K. et al, World J Surg. 2019 Jun;43(6):1404-1415., 6/2019
• Global Initiative for Children’s Surgery: A model of Global Collaboration to advance the Surgical Care of Children.  
  Wright, N. et al, World Jr Surg. 2019 June: 43(6): 1416, 6/2019
• Optimal Resources for Children's Surgical Care: Executive Summary.  
  Global Initiative for Children’s Surgery, World J Surg. 2019 Apr;43(4):978-980, 4/2019
• Strengthening surgery strengthens Health Systems: a new paradigm and potential pathway.  
  Christie SA et al., World J Surgery, 2019; March:43(3):736, 3/2019
• Regarding global pediatric surgery training opportunities. J Pediatr Surg. 2018 Jun; 53(6):1256-1258. PMID: 29605263  
  Baird R, Pandya K, Lal DR, Calkins CM, Oldham KT, Tsai A, Naik-Mathuria B, St-Louis E, Luc MK, LaRusso K, Petroze R, Lofberg KM, Biller CK, Villalona GA, Gourlay DM, K..., J Pediatr Surg. 2018 Jun; 53(6):1256-1258. PMID: 29605263, 7/2018
• Global Surgery: Effective involvement of US Academic Surgery-Report of the American Surgical Association Working Group on Global Surgery  
  Mock C, Debas H, Balch CM, Brennan M, Buyske J, Cusack J, DeMeester S, Herndon D, Holterman A, Jaffe B, Kandil E, Kauffman G, Yang G., (2018) Ann Surg. 268(4):557-583. PMID: 30004921
• An academic career in global surgery: a position paper from the Society of University Surgeons Committee on Academic Global Surgery  
  Krishnaswami S, Stephens C, Yang G, Holterman A. et al. An academic career in global surgery: a position paper from the Society of University Surgeons Committee on Aca..., Surgery. 163: 954-960 PMID: 29254606
• Strengthening Surgery Strengthens Health Systems: A New Paradigm and Potential Pathway for Horizontal Development in Low- and Middle-Income Countries  
  Benedict C. Nwomeh, Sanjay Krishnaswami, Sudha Jayaraman, Anthony Charles, Ai-Xuan L. Holterman, World Journal of Surgery
• Guide to research in academic global surgery: A Statement from the Society of University Surgeons Global Academic Surgery Committee  
  Saluja, S, Nwomeh B, Finlayson S, Holterman A., Jawa S, Jayraman S, Juillard C, Krishnaswami J., et al., (2018) Surgery 163:463-466 PMID: 29221877, 2018
• Global Initiative for Children’s Surgery: A model of Global Collaboration to advance the Surgical Care of Children. (2018) World Jr Surg.  
  Wright N et a., World Jr Surg., 2018
• Growth Hormone Mediates Its Protective Effect in Hepatic Apoptosis through Hnf6. Wang K, et al. PLoS One. 2016.  
  Wang and Holterman, Plos one 2016, 12/2016
• Non Alcoholic Fatty Liver Disease and Bariatric Surgery in Adolescents  
  Holterman A, Guarria J, Tanpure S, Disomma N, Sem Ped Surg, 1/1/2014
• Non Alcoholic Fatty Liver Disease (NAFLD) in Severely Obese Adolescent and Adult patients  
  Holterman A, Guzman G, Fantuzzi G, Huaping Wang H., Browne A, and Holterman M, Obesity, 1/1/2013
• The role of global surgery electives during residency training: Relevance, realities and regulations  
  Axt J, Ntumba PM, Hansen E, Tarpley MJ, Holterman AX, Nadler E, Simeone D, Orloff S, Tarpley JL, Merchant NP, Surgery, 1/1/2013
• Pathophysiological role of HNF6  
  Wang K and Holterman A, Cell Signal, 1/1/2012
• Pediatric obesity  
  Holterman M, Holterman AL and Browne A, Surgical Clinics of North America, 1/1/2012
• INOS/NO signaling regulates apoptosis induced by glycochenodeoxycholate in hepatocytes  
  Wang K, Brems JJ, Gamelli RL and Holterman A, Cell Signal, 1/1/2011
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Books/Book Chapters

• RUSH University Medical Center Review of Surgery 
  Chapter: Pediatric Surgery Review 
  Daley S, and Holterman ALEditors: Velasco, Bines, Deziel, McCarthy, Millikan, Prinz, and Sacclarides.ElsevierEdition 5th,2011
• The Liver, Biology and Pathology 
  Chapter: Gene regulation and in vivo function of Liver Transcription Factors 
  Costa RH, Holterman AL, Rausa F. and Adami GEditors: Arias, Boyer, Fausto, Chisary, Schachter and Shafritz.Edition 4th,2001
• Immunology, Biochemistry and Biotechnology, Volume III , Molecular Mechanisms of Immune Regulation 
  Chapter: T cell recognition of Class I molecules using gene transfection, mutagenesis, and Class I Transgenic mice 
  Engelhard VH, Bernhard EJ, Henderson R, Ridge JP, Strubb S, Holterman MJ, Le AT, Barbosa J, and Lacy EEditors: Tyle P and Srivastava R.VHC Publishers, New York1991
• Transgenic Mice and Mutants in MHC research 
  Chapter: Cytotoxic T cell responses against human Class I molecules in normal and HLA-A2.1 transgenic mice 
  Engelhard VH, Bernhard EJ, Holterman MJ, Le AT, Henderson R, Ridge JP, Strubb S, Barbosa JA and Lacy EEditors: I Igorov and CS David.Springer-Verlag, Berlin1990
• Immunobiology of HLA 
  Chapter: Weak stimulation of murine cytotoxic T cells by human class I molecules maps to the a1 and a2 domains 
  Holterman MJ, Le AT and Engelhard VHEditors: Dupont B.Springer-Verlag, New York1988
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Abstracts/Posters

• Granulocyte-Colony Stimulating Factor (G-CSF) improves hepatic inflammation, fibrosis and attenuates the ductular reaction during biliary obstruction in mice.
  Trinh Van Le, Huy Quang Do, Minh Thanh Dang, Tien-Trieu Pham-Le, Luan Van Tran, Khon Chan Huynh, Ai-Xuan Le Holterman, and Nhung Hai Truong., American Association for the Study of Liver Disease Annual Meeting, Boston, MA, 11/2019
• Pediatric Acute Surgical Support PASS-Piloting a multimodality curriculum for enhancing emergency pediatric surgical capacity at low resources hospitals in Vietnam
  G Barton, K Chen, G Deshpande, T Dinh, C Huy, T Khairallah, S Kryzaniak, C Nguyen, F Nguyen, and A Holterman, Pacific Association of Pediatric Surgeons 2017 conference, Seattle, 1/1/2017
• Pediatric Acute Surgical Support PASS-Initial assessment for the multimodal course for teaching the initial response to pediatric acute surgical emergencies to medical...
  A Holterman, G Barton, K Chen, G Deshpande, T Dinh, T Khairallah, S Kryzaniak, C Nguyen, F Nguyen, C Ta, and T Tra, American Pediatric Surgical Association 49th Annual Meeting, Palm Desert, CA, 5/2018
• Pediatric Acute Surgical Support PASS-Initial assessment for the multimodal course for teaching the initial response to pediatric acute surgical emergencies to medical...
  A Holterman *, G Barton, K Chen, G Deshpande, T Dinh, T Khairallah, S Kryzaniak, C Nguyen, F Nguyen, C Ta, and T Tran., American Pediatric Surgical Association 49th Annual Meeting, Palm Desert, CA, 5/2018
• Hnf6 mediates Growth Hormone protective effects in Hepatic Apoptosis.
  K Wang and A Holterman, American Association for the Study of Liver Disease Annual Meeting, Boston, 11/2016
• Platelet rich plasma enhances adipose-derived mesenchymal stem cell therapeutic effects for liver cirrhosis in mice.
  N Truong, N Nguyen, T Le, H Le, N Huynh, D Ngo, T Nguyen, A Holterman, N Phan, P Pham., American Association for the Study of Liver Disease Annual Meeting, Boston, MA, 11/2016
• IPSAC-VN Pediatric Surgery in Vietnam
  Holterman AL, GICS, Washington D.C., 1/1/2016
• Biliary atresia disease burden in developing countries-a report from Vietnam
  A Holterman, M Liu, H Nguyen, et al., World Federation of Associations of Pediatric Surgeons, Washington D.C., 1/1/2016
• General endotracheal vs. non-Endotracheal Regional Anesthesia for elective inguinal hernia surgery in very preterm neonates: a single institution experience
  J Gurria, P Kuo, L Christensen, and A Holterman, American Pediatric Surgical Association 47th Annual Meeting, San Diego, 1/1/2016
• Regulation of hepatic apoptosis through cIAP1 transcriptional regulation by Hepatocyte Nuclear Factor HNF6 during biliary injury
  Wang K and Holterman A, American Association for the Study of Liver Disease Annual Meeting, San Francisco, 1/1/2009
• Laparoscopic adjustable gastric banding (LAGB) for adolescents in the FDA-IDE trial: An interim report of weight, metabolic and quality of life outcome
  Holterman M, Browne A, Tussing L, Browne A, and Holterman A, American Pediatric Surgical Association 40th Annual Meeting, Fort Myers, FL, 1/1/2009
• The role of the surgeon in the multidisciplinary management of Epidermolysis Bullosa
  Schwartz J, Powell S, Hederman E, Holterman A, 4th Annual Academic Surgical Congress, 70th Annual meeting of the Society of University Surgeons, Sanibel Island, 1/1/2009
• Predictors of Intermediate Outcome in Morbidly Obese Adolescents Undergoing Laparoscopic Adjustable Gastric Banding (LAGB)
  Kruge L, Tussing-Humphreys L, Gao W, Holterman A, Academic Surgical Congress, 4th Annual Academic Surgical Congress, 70th Annual meeting of the Society of University Surgeons, Sanibel Island, 1/1/2009
• GH mediation of hepatocyte transcriptional factor function during bile duct injury in mice
  Holterman A, Minhua Wang, Mike Tallarico, Zorayda Ortiz, American Association for the Study of Liver Disease Annual Meeting, San Francisco, 1/1/2008
• HNF-6 mediates Growth Hormone effects on hepatocyte function during cholestasis
  Wang, M and Holterman A, Academic Surgical Congress 69th Annual meeting of the Society of University Surgeons, Huntington Beach, 1/1/2008
• Vitamin D levels, musculoskeletal problems and physical activity of morbidly obese adolescents undergoing laparoscopic adjustable gastric banding
  Stahl, C, Browne A and Holterman A, Society for Adolescent Medicine, Greensboro, 1/1/2008
• Growth hormone transcriptional activation of HNF-6 (OC-1) regulated hepatic genes during biliary injury in mice
  Wang, M, Chen M, Zheng Q and Holterman A, European Association for the Study of Liver Disease 43rd Annual Meeting, Milan, Italy, 1/1/2008
• A clinical application of exhaled breath analysis in the diagnosis of intestinal injury
  Holterman A and Pleil J, International Society of Breath Odor Research 7th Annual Meeting, Chicago, IL, 1/1/2007
• A rational definition of superobesity for adolescent bariatric patients: BMI> 45kg/m2
  Dillard B, Hering H, Fiscichella P, Holterman M, Browne A, and Holterman A, American Pediatric Surgical Association 38th Annual Meeting, Orlando, FL, 1/1/2007
• Metabolic, Liver Function, and Sleep Parameters in Pediatric and Adult Bariatric Surgery Patients
  R.M. Kutty, A.X. Holterman, S.J. Cotler, J.A. Madura, and J.J. Herdegen, American Thoracic Society International Conference, San Francisco, 1/1/2007
• Effect of the LAPBAND system on comorbid conditions in severely obese adolescents: early results
  AS Gallo, CA Galvani, MV Gorodner, M Holterman, Allen Browne, A Holterman, S Horgan, Society of Gastrointestinal and Endoscopic Surgeons, Las Vegas, NV, 1/1/2007
• Psychological Issues of Adolescents Presenting for Laparoscopic Banding
  Duffecy, J.; Bleil, M.; Labott, S.; Browne,A.; Stahl, C.; Browne, N.; Galvani, C.; Holterman, A. and Holterman, M, 28th Annual meeting for the Society of Behavioral Medicine, Washington, DC, 1/1/2007
• The metabolic syndrome and quality of life in morbidly obese teenagers after laparoscopic adjustable gastric banding. Short term results
  Dillard B, Rink R, Fisichella P, Holterman M, Browne A, Galvani C, Gorodner V, Tussing L, Browne N, Hering H, Labott S, Horgan S and Holterman A, 40th Annual meeting of the Association for Academic surgeons, Phoenix, AZ, 1/1/2007
• The Forkhead Box (Fox) transcription factor Foxo1 attenuates liver injury during biliary obstruction in mice
  Chen M., Zheng G., Wang M., Holterman A, Second Academic Surgical Congress, 68th Annual meeting of the Society of University of Surgeon, Phoenix, AZ, 1/1/2007
• IGF-1 and non IGF-1 mediated mechanisms for Growth Hormone attenuation of liver injury during bile duct ligation in mice
  Chen M, Wang M, Zheng Q and Holterman A, American Association for the Study of Liver Disease Annual Meeting, Boston, CA, 1/1/2006
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Lectures

• Moving forward in treating Biliary atresia- Doing more of the same? 
  International guest speaker, Indonesian Association of Pediatric Surgeons, Padang, October 2018
• Updates on Biliary Atresia-Is it a surgical disease? 
  National meeting of Vietnam Association for Pediatric Surgeons - 10/2018
• Global Innovation in Pediatric Surgery 
  Indonesian Association of Pediatric Surgeons, Balikpapan - 10/2017
• Biliary Atresia- Challenges and Opportunities 
  Aga Khan University, Karachi, Pakistan - 1/1/2017
• Global Innovation in Pediatric Surgery 
  Balikpapan - 1/1/2017
• Pediatric inguinal hernia, hydrocele and undescended testis 
  1/1/2017
• How to enhance liver function during bile duct injury-lessons from mice 
  Harbin Medical University, Harbin, China - 1/1/2017
• IPSAC-VN Pediatric Surgery in Vietnam 
  Washington D.C. - 1/1/2016
• Moving forward in treating Biliary atresia. New concepts and therapies 
  Ninh Binh Hospital for Women and Children - 1/1/2016
• How to enhance liver function during biliary injury-Lessons from mice 
  U of Sciences, HCMC, Vietnam - 1/1/2016
• Biliary Atresia- Challenges and Opportunities in developing countries 
  U of Medicine and Pharmacy, Ho Chi Minh City - 1/1/2015
• Biliary Atresia-challenges and opportunities 
  Carle Foundation Hospital - 1/1/2015
• Surgical Research: why, where, when and how 
  1/1/2014
• Publishing and presenting clinical sciences 
  1/1/2014
• Biliary atresia. The next interventional trial 
  1/1/2014
• Molecular study and treatment of cholestasis-Biliary atresia 
  Shanghai Children's Medical Center - 1/1/2013
• Moving forward in treating Biliary atresia. Doing more of the same? 
  Children's Hospital of Milwaukee - 1/1/2013
• Global Health in developing nations: opportunities and challenges 
  1/1/2013
• Molecular aspects of cholestasis in biliary atresia 
  Ramaiah Academy of Health and Sciences, Bengalore, India - 1/1/2012
• Biliary atresia and future prospects for treatment 
  National Hospital of Pediatrics and Institute of Child Health, Ha Noi, Vietnam - 1/1/2012
• Esophageal atresia- Updates and challenges 
  Children’s Hospital of Illinois - 1/1/2012
• Genome analysis of Biliary Epithelial Cells and hepatocytes 
  Dalian, China - 1/1/2011
• Adapting to the changing faces of Academic Surgery 
  Southern Illinois University - 1/1/2011
• The changing faces of Academic Surgery in the US 
  U of Illinois in Peoria - 1/1/2011
• A U.S. single-institution prospective trial for laparoscopic adjustable gastric banding in morbidly obese adolescents: Metabolic characteristics and intermediate weigh... 
  Nanjing, China - 1/1/2010
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