ChristopherJEarleyMD

Neurology • Baltimore, MD

Sleep Medicine

Professor of Neurology, Johns Hopkins University School of Medicine

Join to view full profile

Dr. Earley is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Earley's full profile

Already have an account?

Office
5501 Hopkins Bayview Circle
Asthma and Allergy Center 1B-82
Baltimore, MD 21224
Phone+1 410-550-0571
Is this information wrong?

Education & Training

University of Virginia Medical CenterResidency, Neurology, 1987 - 1990
Baylor College of MedicineResidency, Internal Medicine, 1984 - 1987
National University of Ireland, Galway Faculty of MedicineClass of 1983

Certifications & Licensure

MD State Medical License 1990 - 2024
NC State Medical License 2020 - 2022
TX State Medical License 1987 - 1991
American Board of Internal Medicine Internal Medicine
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Sleep Science Award in “recognition of outstanding achievements in Sleep Science Research” American Academy of Neurology, 2007
Elected, Fellow in recognition of work in Restless Legs Syndrome. Royal College of Physician, Ireland, 2007
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013-2014

Clinical Trials

Intravenous Iron Metabolism in Restless Legs Syndrome Start of enrollment: 2006 Nov 01
Completed
Phase 2
Glutamate, Hyperarousal and Restless Legs Syndrome Start of enrollment: 2012 Aug 01
Completed

Publications & Presentations

PubMed

Clinical Efficacy and Safety of Intravenous Ferric Carboxymaltose for Treatment of Restless Legs Syndrome: A Multicenter, Randomized, Placebo-controlled Clinical Trial.
Diego García-Borreguero, Mark Falone, Christopher J Earley, John W Winkelman> ;Sleep. 2024 Apr 16
A randomized double-blind pilot study to evaluate the efficacy, safety, and tolerability of intravenous iron versus oral iron for the treatment of restless legs syndro...
Vanessa Short, Richard Allen, Christopher J Earley, Huzefa Bahrain, Stella Rineer, Kiumarce Kashi, Jesse Gerb, Michael Auerbach> ;American Journal of Hematology. 2024 Mar 13
On the optimization of 3D inflow-based vascular-space-occupancy (iVASO) MRI for the quantification of arterial cerebral blood volume (CBVa).
Chunming Gu, Yinghao Li, Di Cao, Xinyuan Miao, Adrian G Paez, Yuanqi Sun, Jitong Cai, Wenbo Li, Xu Li, Jay J Pillai, Christopher J Earley, Peter C M van Zijl, Jun Hua> ;Magnetic Resonance in Medicine. 2024 May 1
1 citations
Restless legs syndrome, neuroleptic-induced akathisia, and opioid-withdrawal restlessness: shared neuronal mechanisms?
Sergi Ferré, John W Winkelman, Diego García-Borreguero, Annabelle M Belcher, Joy H Chang, Christopher J Earley> ;Sleep. 2024 Mar 11
1 citations
Ferric carboxymaltose effects on restless legs syndrome and on brain iron in patients with iron deficiency anemia.
Hyoeun Bae, Yong Won Cho, Keun Tae Kim, Xu Li, Christopher J Earley> ;Sleep Medicine. 2023 Sep 1
10 citations
Brain-iron deficiency models of restless legs syndrome.
Christopher J Earley, Byron C Jones, Sergi Ferré> ;Experimental Neurology. 2022 Oct 1
9 citations
Brain Iron Deficiency Changes the Stoichiometry of Adenosine Receptor Subtypes in Cortico-Striatal Terminals: Implications for Restless Legs Syndrome.
Matilde S Rodrigues, Samira G Ferreira, César Quiroz, Christopher J Earley, Diego García-Borreguero, Rodrigo A Cunha, Francisco Ciruela, Attila Köfalvi, Sergi Ferré> ;Molecules. 2022 Feb 23
8 citations
Functional and pharmacological role of the dopamine Dreceptor and its polymorphic variants.
Sergi Ferré, Annabelle M Belcher, Jordi Bonaventura, César Quiroz, Marta Sánchez-Soto, Verònica Casadó-Anguera, Ning-Sheng Cai, Estefanía Moreno, Comfort A Boateng, Th...> ;Frontiers in Endocrinology. 2022 Jan 1
2 citations
The Safety and Efficacy of Pregabalin Add-on Therapy in Restless Legs Syndrome Patients
Hyoeun Bae, Yong Won Cho, Keun Tae Kim, Richard P. Allen, Christopher J. Earley> ;Frontiers in Neurology. 2021 Nov 29
6 citations
Randomized, placebo-controlled trial of ferric carboxymaltose in restless legs syndrome patients with iron deficiency anemia.
Hyoeun Bae, Yong Won Cho, Keun Tae Kim, Richard P. Allen, Christopher J. Earley> ;Sleep Medicine. 2021 Aug 1
43 citations
The Management of Restless Legs Syndrome: An Updated Algorithm.
Michael H. Silber, Mark J. Buchfuhrer, Christopher J. Earley, Brian B. Koo, Mauro Manconi, John W. Winkelman, Phillip M. Becker, J. Andrew Berkowski, Stefan Clemens, J...> ;Mayo Clinic Proceedings. 2021 Jul 1
8 citations
Akathisia and Restless Legs Syndrome: Solving the Dopaminergic Paradox.
Sergi Ferré, Xavier Guitart, César Quiroz, William Rea, Celia Garcia-Malo, Diego Garcia-Borreguero, Richard P. Allen, Christopher J. Earley> ;Sleep Medicine Clinics. 2021 Apr 10
13 citations
We need to do better: A systematic review and meta-analysis of diagnostic test accuracy of restless legs syndrome screening instruments.
Stephany Fulda, Richard P. Allen, Christopher J. Earley, Birgit Högl, Diego Garcia-Borreguero, Yuichi Inoue, William G. Ondo, Arthur S. Walters, Anne Marie Williams, J...> ;Sleep Medicine Reviews. 2021 Mar 13
4 citations
Developing a biomarker for restless leg syndrome using genome wide DNA methylation data.
Arunima Roy, Christopher J. Earley, Richard P. Allen, Zachary Kaminsky> ;Sleep Medicine. 2021 Feb 1
In memoriam: Richard P. Allen.
Christopher J. Earley> ;Sleep Medicine. 2021 Jan 7
4 citations
Developing a behavioral model of Restless Legs Syndrome utilizing mice with natural variances in ventral midbrain iron.
Christopher J. Earley, Richard P. Allen, Byron C. Jones, Erica L. Unger> ;Sleep Medicine. 2020 Jul 1
2 citations
Effects of new PLM scoring rules on PLM rate in relation to sleep and resting wake for RLS and healthy controls.
Hughes Elena, Bruni Leslie, Patrick Skeba, A. Wang, Christopher J. Earley, Richard P. Allen> ;Sleep & Breathing = Schlaf & Atmung. 2021 Mar 1
2 citations
Pilot study: can machine learning analyses of movement discriminate between leg movements in sleep (LMS) with vs. without cortical arousals?
Amitanshu Jha, Nilanjan Banerjee, Cody Feltch, Ryan Robucci, Christopher J. Earley, Janet Lam, Richard P. Allen> ;Sleep & Breathing = Schlaf & Atmung. 2021 Mar 1
7 citations
Evidence for communication of peripheral iron status to cerebrospinal fluid: clinical implications for therapeutic strategy
James R. Connor, Kari A. Duck, Stephanie M. Patton, Ian A. Simpson, Lynn Marie Trotti, Richard P. Allen, Christopher J. Earley, David B. Rye> ;Fluids and Barriers of the CNS. 2020 Apr 16
9 citations
Moderate to severe but not mild RLS is associated with greater sleep-related sympathetic autonomic activation than healthy adults without RLS.
Byungjoo Jin, A. Wang, Christopher J. Earley, Richard P. Allen> ;Sleep Medicine. 2020 Apr 1
10 citations
Resting-state connectivity and the effects of treatment in restless legs syndrome.
Yeong Seon Lee, Jeonghun Ku, Keun Tae Kim, Hyuk Won Chang, Christopher J. Earley, Richard P. Allen, Yong Won Cho> ;Sleep Medicine. 2020 Mar 1
11 citations
Iron-deficiency and dopaminergic treatment effects on RLS-Like behaviors of an animal model with the brain iron deficiency pattern of the restless legs syndrome.
Richard P. Allen, Christopher J. Earley, Byron C. Jones, Erica L. Unger> ;Sleep Medicine. 2020 Feb 5
12 citations
Extracellular vesicles reveal abnormalities in neuronal iron metabolism in restless legs syndrome
Sahil Chawla, Seema Gulyani, Richard P. Allen, Christopher J. Earley, Xu Li, Peter C.M. van Zijl, Dimitrios Kapogiannis> ;Sleep. 2019 Jul 8
72 citations
New Insights into the Neurobiology of Restless Legs Syndrome.
Sergi Ferré, Diego Garcia-Borreguero, Richard P. Allen, Christopher J. Earley> ;The Neuroscientist. 2019 Apr 1
3 citations
Assessment of change in restless legs syndrome symptoms during the acute drug-withdrawal period.
A. Wang, Patrick Skeba, Christopher J. Earley, Richard P. Allen, Foster, K., Keyana Foster, Kasidet Hiranniramol> ;Sleep Medicine. 2018 Aug 17
Join now to see all

Hospital Affiliations

Johns Hopkins HospitalBaltimore, Maryland
Johns Hopkins Bayview Medical CenterBaltimore, Maryland

External Links

Johns Hopkins Physicianshttp://www.hopkinsmedicine.org/christopher-earley